Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   GPW69_RS02075 Genome accession   NZ_LR738724
Coordinates   401902..402543 (+) Length   213 a.a.
NCBI ID   WP_074391007.1    Uniprot ID   -
Organism   Streptococcus suis isolate 9401240     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 396902..407543
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW69_RS02055 - 397202..397939 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  GPW69_RS02060 pknB 397939..399468 (+) 1530 Protein_366 Stk1 family PASTA domain-containing Ser/Thr kinase -
  GPW69_RS10895 - 399469..399933 (+) 465 Protein_367 PASTA domain-containing protein -
  GPW69_RS02065 liaF 400222..400917 (+) 696 WP_024384079.1 cell wall-active antibiotics response protein LiaF -
  GPW69_RS02070 - 400914..401930 (+) 1017 WP_002937028.1 sensor histidine kinase -
  GPW69_RS02075 vraR 401902..402543 (+) 642 WP_074391007.1 response regulator transcription factor Regulator
  GPW69_RS02080 - 402593..403993 (+) 1401 WP_024377222.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  GPW69_RS02085 - 403995..404366 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  GPW69_RS02090 cysK 404392..405318 (-) 927 WP_002937015.1 cysteine synthase A -
  GPW69_RS02095 - 405408..406040 (-) 633 WP_044769501.1 YigZ family protein -
  GPW69_RS02100 comFA/cflA 406097..407389 (+) 1293 WP_074391009.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23732.32 Da        Isoelectric Point: 5.0067

>NTDB_id=1007133 GPW69_RS02075 WP_074391007.1 401902..402543(+) (vraR) [Streptococcus suis isolate 9401240]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADASFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=1007133 GPW69_RS02075 WP_074391007.1 401902..402543(+) (vraR) [Streptococcus suis isolate 9401240]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTAGAGGTTAAACCCGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAGTGGCCGCAAGCGCAGATT
GTTATCCTGACCTCCTACCTAGATAATGAAAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGCGTCATTCATATCCTTAAAAACTGTTAAAACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTGAGCGACCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

55.072

97.183

0.535
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413

Multiple sequence alignment