Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   FJH52_RS07645 Genome accession   NZ_LR595848
Coordinates   1530017..1530694 (-) Length   225 a.a.
NCBI ID   WP_000548959.1    Uniprot ID   Q9S1K2
Organism   Streptococcus pneumoniae strain 4559 isolate 4559     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1525017..1535694
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FJH52_RS07625 - 1525178..1525807 (-) 630 WP_000762083.1 NAD(P)-dependent oxidoreductase -
  FJH52_RS11500 - 1526046..1526420 (+) 375 Protein_1525 hypothetical protein -
  FJH52_RS07630 - 1526677..1527000 (+) 324 WP_000422779.1 MazG-like protein -
  FJH52_RS07635 thrS 1527058..1529001 (+) 1944 WP_000608356.1 threonine--tRNA ligase -
  FJH52_RS07640 - 1529050..1530024 (-) 975 WP_000887954.1 HAMP domain-containing histidine kinase -
  FJH52_RS07645 braR 1530017..1530694 (-) 678 WP_000548959.1 response regulator transcription factor Regulator
  FJH52_RS07650 - 1530850..1531923 (+) 1074 WP_001273828.1 DUF2974 domain-containing protein -
  FJH52_RS07655 - 1532014..1532317 (-) 304 Protein_1531 hypothetical protein -
  FJH52_RS07660 - 1532386..1532823 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  FJH52_RS07665 - 1532899..1533741 (-) 843 WP_000160943.1 metallophosphoesterase -
  FJH52_RS07670 - 1533853..1534503 (+) 651 WP_000188505.1 metal-dependent transcriptional regulator -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25964.16 Da        Isoelectric Point: 5.1362

>NTDB_id=1006296 FJH52_RS07645 WP_000548959.1 1530017..1530694(-) (braR) [Streptococcus pneumoniae strain 4559 isolate 4559]
MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=1006296 FJH52_RS07645 WP_000548959.1 1530017..1530694(-) (braR) [Streptococcus pneumoniae strain 4559 isolate 4559]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGATTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1K2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

35.319

100

0.369