Detailed information NTG1005784

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXQ44_RS10440
• Genome accession: NZ_CP157308
• Coordinates: 2078765..2079808 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN82
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2073765..2084808

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ44_RS10410 (UXQ44_10410)	-	2074183..2075439 (-)	1257	WP_001795438.1	aminopeptidase	-
UXQ44_RS10415 (UXQ44_10415)	-	2075442..2075642 (-)	201	WP_000180461.1	DUF1128 family protein	-
UXQ44_RS10420 (UXQ44_10420)	-	2075789..2076253 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXQ44_RS10425 (UXQ44_10425)	-	2076260..2076535 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXQ44_RS10430 (UXQ44_10430)	-	2076813..2078030 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
UXQ44_RS10435 (UXQ44_10435)	vraR	2078146..2078775 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
UXQ44_RS10440 (UXQ44_10440)	vraS	2078765..2079808 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXQ44_RS10445 (UXQ44_10445)	liaF	2079805..2080506 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXQ44_RS10450 (UXQ44_10450)	-	2080521..2080907 (-)	387	WP_001110179.1	hypothetical protein	-
UXQ44_RS10455 (UXQ44_10455)	map	2081124..2081882 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
UXQ44_RS10460 (UXQ44_10460)	-	2082469..2083455 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
UXQ44_RS10465 (UXQ44_10465)	-	2083886..2084299 (-)	414	WP_001549145.1	hypothetical protein	-
UXQ44_RS10470 (UXQ44_10470)	-	2084328..2084438 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1005784 UXQ44_RS10440 WP_001017131.1 2078765..2079808(-) (vraS) [Staphylococcus aureus strain BSN82]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1005784 UXQ44_RS10440 WP_001017131.1 2078765..2079808(-) (vraS) [Staphylococcus aureus strain BSN82]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1