Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   FGL05_RS06710 Genome accession   NZ_LR594044
Coordinates   1366835..1367479 (-) Length   214 a.a.
NCBI ID   WP_020916314.1    Uniprot ID   A0AB33AKG7
Organism   Streptococcus lutetiensis strain NCTC8796     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1361835..1372479
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL05_RS06685 (NCTC8796_01421) comFA/cflA 1361848..1363146 (-) 1299 WP_020916319.1 DEAD/DEAH box helicase Machinery gene
  FGL05_RS06690 (NCTC8796_01422) - 1363201..1363827 (+) 627 WP_111712652.1 YigZ family protein -
  FGL05_RS06695 (NCTC8796_01423) cysK 1363927..1364856 (+) 930 WP_020916317.1 cysteine synthase A -
  FGL05_RS06700 (NCTC8796_01424) - 1364955..1365311 (-) 357 WP_020916316.1 S1 RNA-binding domain-containing protein -
  FGL05_RS09615 (NCTC8796_01425) - 1365311..1366711 (-) 1401 WP_081048448.1 Cof-type HAD-IIB family hydrolase -
  FGL05_RS06710 (NCTC8796_01426) vraR 1366835..1367479 (-) 645 WP_020916314.1 response regulator transcription factor Regulator
  FGL05_RS06715 (NCTC8796_01427) - 1367463..1368488 (-) 1026 WP_020916313.1 sensor histidine kinase -
  FGL05_RS06720 (NCTC8796_01428) liaF 1368485..1369180 (-) 696 WP_058813684.1 cell wall-active antibiotics response protein LiaF -
  FGL05_RS06725 (NCTC8796_01429) stkP/pknB 1369281..1371194 (-) 1914 WP_058813683.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  FGL05_RS06730 (NCTC8796_01430) - 1371194..1371931 (-) 738 WP_043894973.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24009.84 Da        Isoelectric Point: 5.0404

>NTDB_id=1005587 FGL05_RS06710 WP_020916314.1 1366835..1367479(-) (vraR) [Streptococcus lutetiensis strain NCTC8796]
MAQKIRVILVDDHEMVRLGLKSFFNLQPDVEVIGEAGNGIDGIKLALDLKPDVVVMDLVMPEMSGVEATLKLLKEWKEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIQKVARGELAIETEVDKKIKAHDQRPELHEDLTARERDILRLL
AKGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFKHHLVPQDED

Nucleotide


Download         Length: 645 bp        

>NTDB_id=1005587 FGL05_RS06710 WP_020916314.1 1366835..1367479(-) (vraR) [Streptococcus lutetiensis strain NCTC8796]
ATGGCCCAGAAAATTAGAGTTATCCTAGTTGATGATCATGAAATGGTGCGTCTTGGTTTGAAAAGTTTTTTTAACTTGCA
ACCAGATGTTGAAGTTATTGGCGAAGCAGGAAATGGAATTGACGGAATTAAACTTGCTTTAGACTTAAAACCAGATGTCG
TAGTGATGGATTTGGTGATGCCTGAAATGAGTGGTGTTGAAGCGACCTTAAAACTCTTAAAAGAGTGGAAAGAAGCTAAA
ATCCTTGTTCTGACATCTTATCTTGATAATGAAAAAATCTATCCAGTTATTGAAGCAGGTGCTAAAGGTTATATGTTAAA
AACATCTAGTGCCGCTGAAATTCTTAACGCTATTCAGAAAGTAGCACGTGGTGAACTAGCAATCGAAACAGAAGTCGATA
AGAAAATCAAAGCACACGATCAAAGACCTGAATTGCATGAGGATTTGACAGCGCGTGAGCGAGATATTTTAAGACTTTTA
GCCAAAGGTTATGATAATCAGACTATTGCTGATGAACTGTTTATTTCGTTAAAAACCGTTAAAACACACGTTTCAAATAT
CTTGGCTAAGCTAGAAGTGGATGACCGTACACAAGCGGTTGTCTATGCCTTTAAGCATCATTTAGTACCGCAAGATGAGG
ATTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-119)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0AB33AKG7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.456

96.262

0.495
  degU Bacillus subtilis subsp. subtilis str. 168

37.054

100

0.388