Detailed information NTG1005564

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXR68_RS09060
• Genome accession: NZ_CP157301
• Coordinates: 1873199..1874242 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN84
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1868199..1879242

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR68_RS09030 (UXR68_09030)	-	1868620..1869876 (-)	1257	WP_001793428.1	aminopeptidase	-
UXR68_RS09035 (UXR68_09035)	-	1869879..1870079 (-)	201	WP_000180460.1	DUF1128 family protein	-
UXR68_RS09040 (UXR68_09040)	-	1870226..1870690 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXR68_RS09045 (UXR68_09045)	-	1870697..1870972 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXR68_RS09050 (UXR68_09050)	-	1871250..1872467 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
UXR68_RS09055 (UXR68_09055)	vraR	1872580..1873209 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
UXR68_RS09060 (UXR68_09060)	vraS	1873199..1874242 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXR68_RS09065 (UXR68_09065)	liaF	1874239..1874940 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXR68_RS09070 (UXR68_09070)	-	1874955..1875341 (-)	387	WP_001110182.1	hypothetical protein	-
UXR68_RS09075 (UXR68_09075)	map	1875558..1876316 (-)	759	WP_000636145.1	type I methionyl aminopeptidase	-
UXR68_RS09080 (UXR68_09080)	-	1876790..1877776 (+)	987	WP_000999712.1	aromatic acid exporter family protein	-
UXR68_RS09085 (UXR68_09085)	-	1877965..1878378 (-)	414	WP_025174370.1	hypothetical protein	-
UXR68_RS09090 (UXR68_09090)	-	1878407..1878517 (-)	111	WP_014937049.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1005564 UXR68_RS09060 WP_001017131.1 1873199..1874242(-) (vraS) [Staphylococcus aureus strain BSN84]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1005564 UXR68_RS09060 WP_001017131.1 1873199..1874242(-) (vraS) [Staphylococcus aureus strain BSN84]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1