Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   FGK95_RS10045 Genome accession   NZ_LR590625
Coordinates   2022598..2024580 (-) Length   660 a.a.
NCBI ID   WP_039994902.1    Uniprot ID   -
Organism   Streptococcus canis strain B700072     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2017598..2029580
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK95_RS10020 (SAMEA5186854_02013) cinA 2018443..2019714 (-) 1272 WP_093999150.1 competence/damage-inducible protein A Machinery gene
  FGK95_RS11025 - 2019831..2019989 (-) 159 WP_223824822.1 VOC family protein -
  FGK95_RS10030 (SAMEA5186854_02015) - 2020187..2020759 (-) 573 WP_003045731.1 DNA-3-methyladenine glycosylase I -
  FGK95_RS10035 (SAMEA5186854_02016) ruvA 2020769..2021365 (-) 597 WP_003045733.1 Holliday junction branch migration protein RuvA Machinery gene
  FGK95_RS10040 (SAMEA5186854_02017) - 2021349..2022587 (-) 1239 WP_003045734.1 MDR family MFS transporter -
  FGK95_RS10045 (SAMEA5186854_02018) hexB 2022598..2024580 (-) 1983 WP_039994902.1 DNA mismatch repair endonuclease MutL Machinery gene
  FGK95_RS10945 - 2024674..2025586 (-) 913 Protein_1904 tyrosine-type recombinase/integrase -
  FGK95_RS10070 (SAMEA5186854_02021) - 2026213..2026788 (-) 576 WP_093999153.1 TMEM175 family protein -
  FGK95_RS10075 (SAMEA5186854_02022) - 2026849..2027337 (-) 489 WP_138114355.1 prolyl-tRNA synthetase associated domain-containing protein -
  FGK95_RS10080 (SAMEA5186854_02023) - 2027372..2028004 (-) 633 WP_093999155.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 660 a.a.        Molecular weight: 74407.98 Da        Isoelectric Point: 5.7465

>NTDB_id=1004881 FGK95_RS10045 WP_039994902.1 2022598..2024580(-) (hexB) [Streptococcus canis strain B700072]
MTNIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQITIEIEESGLKMIQITDNGEGMSHEDLPLSLRRHATSK
IKSQSDLFRIRTLGFRGEALPSVASISKITIKTATKEAIHGSILVATGGKIETLEPISTPIGTKIKVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTAKKMIAISNADLDFEVSGYVSLP
ELTRANRNYMTILINGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIAIQLDPYLADVNVHPTKQEVRISKERELMALISA
AISESLREQDLIPDALENLAKSSTRHFSKPEQTQLPLQSRGLYYDPQKNDFFVKESAVAEKMPETDFHYGDVDNCVKVEK
TESLPHSEEDTGPSSVKHASRPQDSLVNPDHPDFDLKNKQKLSQMLDRLENEEKSAFPELDYFGQMHGTYLFAQGKDGLF
IIDQHAAQERVKYEYYRDKIGDVDSSLQQLLVPYLFEFSGSDFINLQEKMTLLNEVGIFLEVYGHNTFILREHPIWMKEE
EIESGVYEMCDMLLLTNEVSVKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYNCPHGRPVLINFSKADM
EKMFRRIQENHTSLRELGKY

Nucleotide


Download         Length: 1983 bp        

>NTDB_id=1004881 FGK95_RS10045 WP_039994902.1 2022598..2024580(-) (hexB) [Streptococcus canis strain B700072]
ATGACAAACATTATTGAATTACCGGAAGTTCTCGCCAACCAAATCGCAGCTGGTGAGGTTGTAGAAAGACCAGCAAGTGT
TGTCAAGGAGTTGGTTGAGAATGCTATTGATGCTAAAAGTAGCCAGATTACCATTGAAATTGAAGAGTCTGGCCTTAAAA
TGATACAGATTACAGACAATGGTGAAGGGATGTCACACGAAGACCTACCCTTGAGTTTGCGTCGTCATGCCACCAGTAAA
ATTAAAAGTCAGAGTGACCTTTTTCGAATTAGGACGCTTGGATTTCGAGGAGAAGCTTTACCGTCGGTTGCCTCCATTAG
TAAAATCACGATAAAAACTGCAACAAAAGAAGCTATACATGGCTCTATTCTCGTTGCTACGGGTGGGAAAATTGAGACGC
TTGAACCAATCTCAACACCTATTGGAACTAAAATTAAGGTTGAAAACCTTTTTTACAACACTCCTGCCCGCCTCAAATAC
ATGAAAAGTTTACAGGCAGAATTAGCTCACATTGTAGATGTGGTCAATCGGTTGAGTTTGGCTCACCCAGAAGTTGCTTT
TACACTGATTAGTGATGGTCGTCAATTAACTCAGACCTCAGGGACTGGCGATTTGCGCCAAGCTATTGCTGGTATTTACG
GCTTGAATACTGCGAAGAAAATGATTGCTATCTCTAATGCTGATCTGGATTTTGAAGTGTCTGGATATGTCAGTTTACCA
GAGTTGACACGTGCTAATCGAAACTATATGACAATTTTAATCAACGGACGCTACATTAAAAACTTCTTGCTCAATCGAGC
TATCTTAGATGGTTATGGTTCTAAATTGATGGTTGGACGTTTTCCGATTGTTGTGATTGCTATTCAGCTTGATCCTTACT
TAGCTGATGTCAATGTGCACCCCACAAAGCAAGAGGTTCGTATTTCAAAAGAGCGTGAGTTGATGGCTTTAATCAGTGCA
GCTATTTCTGAAAGCCTTAGGGAACAAGATTTAATTCCAGATGCACTTGAAAATTTAGCTAAATCAAGCACACGACATTT
TTCCAAACCAGAGCAAACACAACTTCCTTTACAGTCTAGGGGACTTTACTATGATCCGCAAAAGAATGACTTTTTTGTCA
AAGAATCGGCTGTCGCGGAAAAAATGCCTGAAACTGATTTTCATTACGGCGATGTTGACAACTGTGTAAAGGTTGAAAAG
ACAGAGTCGCTACCTCACTCAGAAGAAGACACAGGACCTTCTTCAGTAAAGCATGCTAGCCGTCCCCAAGATAGTTTAGT
GAATCCTGATCATCCTGACTTTGACTTAAAAAATAAACAGAAGTTATCTCAAATGTTGGATCGCTTGGAAAATGAAGAAA
AATCAGCATTTCCTGAATTGGATTATTTTGGTCAGATGCATGGGACCTATCTTTTTGCTCAAGGCAAAGATGGTTTATTT
ATCATTGACCAACACGCTGCCCAAGAGCGGGTTAAATATGAATATTATCGTGATAAGATTGGCGATGTTGACAGTAGTTT
ACAGCAGTTGTTAGTGCCTTACTTATTTGAGTTTTCTGGTTCTGATTTCATTAATTTACAGGAAAAAATGACACTCTTAA
ATGAAGTCGGTATCTTTCTGGAAGTTTATGGGCACAATACTTTCATTCTGAGGGAACACCCTATCTGGATGAAAGAAGAA
GAGATTGAATCTGGTGTCTATGAAATGTGTGATATGTTACTTTTGACAAATGAGGTATCTGTCAAAACTTATCGAGCAGA
GTTAGCGATTATGATGAGCTGTAAACGGTCTATTAAAGCTAATCACAGTTTAGATGATTATTCAGCAAGGAATCTTTTGC
TGCAATTAGCGCAATGCCAAAATCCTTATAACTGTCCTCATGGCAGACCCGTTTTGATTAACTTTAGCAAGGCAGATATG
GAAAAAATGTTCCGTCGTATCCAAGAAAATCATACTAGTCTACGAGAATTAGGAAAATATTAG

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(462-604)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

68.477

100

0.688

Multiple sequence alignment