Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   FGK91_RS00680 Genome accession   NZ_LR590483
Coordinates   104638..104922 (+) Length   94 a.a.
NCBI ID   WP_032465969.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8318     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 99638..109922
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK91_RS00655 (NCTC8318_00132) - 101584..101949 (+) 366 WP_002986560.1 DUF1033 family protein -
  FGK91_RS00660 (NCTC8318_00133) comGA 102042..102980 (+) 939 WP_023079010.1 competence type IV pilus ATPase ComGA Machinery gene
  FGK91_RS00665 (NCTC8318_00134) comGB 102916..103950 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  FGK91_RS00670 (NCTC8318_00135) comGC 103952..104278 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  FGK91_RS00675 (NCTC8318_00136) comGD 104253..104681 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  FGK91_RS00680 (NCTC8318_00137) comGE 104638..104922 (+) 285 WP_032465969.1 competence type IV pilus minor pilin ComGE Machinery gene
  FGK91_RS00685 (NCTC8318_00138) comGF 104915..105349 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  FGK91_RS00690 (NCTC8318_00139) comGG 105333..105659 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  FGK91_RS00695 (NCTC8318_00140) comGH 105757..106710 (+) 954 WP_010921802.1 class I SAM-dependent methyltransferase Machinery gene
  FGK91_RS00700 (NCTC8318_00141) - 106769..107965 (+) 1197 WP_023078999.1 acetate kinase -
  FGK91_RS00705 - 108151..108459 (+) 309 WP_030126458.1 hypothetical protein -
  FGK91_RS00710 (NCTC8318_00142) proC 108542..109312 (-) 771 WP_023078993.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 94 a.a.        Molecular weight: 10660.57 Da        Isoelectric Point: 8.9043

>NTDB_id=1004703 FGK91_RS00680 WP_032465969.1 104638..104922(+) (comGE) [Streptococcus pyogenes strain NCTC8318]
MGIIKKQVKAYIALESMIATGTLFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEMTLNGCHITILRTDRY
ISIHDDEGEVMKIE

Nucleotide


Download         Length: 285 bp        

>NTDB_id=1004703 FGK91_RS00680 WP_032465969.1 104638..104922(+) (comGE) [Streptococcus pyogenes strain NCTC8318]
GTGGGAATTATCAAAAAACAAGTCAAAGCTTACATAGCCCTTGAAAGTATGATCGCAACAGGCACCCTCTTTAGTATTGT
CATTCTTGTCTTAAGTAGTTTACAGCAGAGTCAGGCTGCTCTAACGTACTATCGAAAGCAGCAAGAAAAGCTTAATCTAG
CCTTGATGGCAGTACAAACTAGAACTAAAGAGATGACATTGAATGGTTGTCATATTACTATTTTACGTACGGATAGATAC
ATTAGTATTCACGATGACGAAGGAGAAGTGATGAAGATTGAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(12-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Lactococcus lactis subsp. cremoris KW2

38.298

100

0.383