Detailed information NTG1004474

Bioinformatically predicted

Overview

• Name: braR
• Type: Regulator
• Locus tag: E0F34_RS07430
• Genome accession: NZ_LR536843
• Coordinates: 1363020..1363697 (-)
• Length: 225 a.a.
• NCBI ID: WP_000548957.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1358020..1368697

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0F34_RS07390 (SAMEA104035599_01402)	-	1358181..1358810 (-)	630	WP_000762087.1	NAD(P)-dependent oxidoreductase	-
E0F34_RS07395 (SAMEA104035599_01403)	-	1359049..1359249 (+)	201	WP_001826938.1	hypothetical protein	-
E0F34_RS07410 (SAMEA104035599_01405)	-	1359680..1359820 (+)	141	WP_061649899.1	hypothetical protein	-
E0F34_RS07415	-	1359827..1360003 (+)	177	WP_000166031.1	MazG-like protein	-
E0F34_RS07420 (SAMEA104035599_01406)	thrS	1360061..1362004 (+)	1944	WP_000608349.1	threonine--tRNA ligase	-
E0F34_RS07425 (SAMEA104035599_01407)	-	1362053..1363027 (-)	975	WP_000887954.1	HAMP domain-containing histidine kinase	-
E0F34_RS07430 (SAMEA104035599_01408)	braR	1363020..1363697 (-)	678	WP_000548957.1	response regulator transcription factor	Regulator
E0F34_RS07435 (SAMEA104035599_01409)	-	1363853..1364926 (+)	1074	WP_001273825.1	DUF2974 domain-containing protein	-
E0F34_RS07440 (SAMEA104035599_01410)	-	1365017..1365319 (-)	303	WP_000281594.1	hypothetical protein	-
E0F34_RS07445 (SAMEA104035599_01411)	-	1365388..1365825 (-)	438	WP_001166786.1	Rrf2 family transcriptional regulator	-
E0F34_RS07450 (SAMEA104035599_01412)	-	1365901..1366743 (-)	843	WP_000160955.1	metallophosphoesterase family protein	-
E0F34_RS07455 (SAMEA104035599_01413)	-	1366855..1367505 (+)	651	WP_000188505.1	metal-dependent transcriptional regulator	-
E0F34_RS07465 (SAMEA104035599_01414)	-	1367682..1368194 (+)	513	WP_061714073.1	hypothetical protein	-

Sequence

Protein

• Length: 225 a.a.
• Molecular weight: 25964.16 Da
• Isoelectric Point: 5.1362

>NTDB_id=1004474 E0F34_RS07430 WP_000548957.1 1363020..1363697(-) (braR) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSIFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide

• Length: 678 bp

>NTDB_id=1004474 E0F34_RS07430 WP_000548957.1 1363020..1363697(-) (braR) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGATTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTATATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCCAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (4-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (147-221)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braR	Staphylococcus aureus N315	49.083	96.889	0.476
vicR	Streptococcus mutans UA159	35.319	100	0.369