Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   E0F40_RS10295 Genome accession   NZ_LR216065
Coordinates   1899649..1900455 (+) Length   268 a.a.
NCBI ID   WP_000090700.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain GPSC18 substr. ST13 isolate 55896440-41bd-11e5-998e-3c4a9275d6c6     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1894649..1905455
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F40_RS10245 (SAMEA3714487_01949) - 1894727..1894957 (-) 231 WP_000192920.1 hypothetical protein -
  E0F40_RS11810 (SAMEA3714487_01951) - 1895077..1895220 (-) 144 WP_000161124.1 hypothetical protein -
  E0F40_RS10250 (SAMEA3714487_01952) - 1895207..1895467 (-) 261 WP_000471463.1 hypothetical protein -
  E0F40_RS10255 (SAMEA3714487_01953) - 1895460..1895666 (-) 207 WP_000839221.1 hypothetical protein -
  E0F40_RS11815 (SAMEA3714487_01954) - 1895666..1895827 (-) 162 WP_000823400.1 BOW99_gp33 family protein -
  E0F40_RS10265 (SAMEA3714487_01956) - 1896045..1896899 (-) 855 WP_001198473.1 ATP-binding protein -
  E0F40_RS10270 (SAMEA3714487_01957) - 1896909..1897760 (-) 852 WP_050167223.1 DnaD domain protein -
  E0F40_RS10275 (SAMEA3714487_01958) - 1897757..1897984 (-) 228 WP_001125555.1 helix-turn-helix domain-containing protein -
  E0F40_RS10285 (SAMEA3714487_01960) - 1898175..1898465 (-) 291 WP_001815531.1 hypothetical protein -
  E0F40_RS11820 - 1898462..1898608 (-) 147 WP_000389580.1 hypothetical protein -
  E0F40_RS12365 (SAMEA3714487_01961) - 1899003..1899125 (-) 123 WP_000343850.1 hypothetical protein -
  E0F40_RS10290 (SAMEA3714487_01962) - 1899199..1899474 (-) 276 WP_001094372.1 hypothetical protein -
  E0F40_RS10295 (SAMEA3714487_01963) irvR 1899649..1900455 (+) 807 WP_000090700.1 XRE family transcriptional regulator Regulator
  E0F40_RS10300 (SAMEA3714487_01964) - 1900457..1901221 (+) 765 WP_000032361.1 type II toxin-antitoxin system PemK/MazF family toxin -
  E0F40_RS10305 (SAMEA3714487_01965) - 1901500..1902945 (+) 1446 WP_050105991.1 recombinase family protein -
  E0F40_RS10315 (SAMEA3714487_01966) comGB/cglB 1903027..1904043 (-) 1017 WP_077141332.1 competence type IV pilus assembly protein ComGB Machinery gene
  E0F40_RS10320 (SAMEA3714487_01967) comGA/cglA/cilD 1903991..1904932 (-) 942 WP_000249550.1 competence type IV pilus ATPase ComGA Machinery gene
  E0F40_RS10325 (SAMEA3714487_01968) - 1905008..1905373 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 268 a.a.        Molecular weight: 30233.61 Da        Isoelectric Point: 4.5137

>NTDB_id=1004142 E0F40_RS10295 WP_000090700.1 1899649..1900455(+) (irvR) [Streptococcus pneumoniae strain GPSC18 substr. ST13 isolate 55896440-41bd-11e5-998e-3c4a9275d6c6]
MARGRGKLTPQDKEDMKVFSANLNSILSDRNCKQAELSRATGIPPSTLTGYVKGTSLPIPGNVQKIADFFGVPKSVLDPR
FVTNNSMVDDSSSNTSSIQTIYDQLEPPRQGKVLNYAKRQLKEQRNEEETKINEVSENIIRLDDYRQTTYRRVTGVVSAG
SGSIQDDDLDMEVSFYEDEIPDDYDAIAYVVGNSMEPKIKNGDYLFIKNTQQVDYNTIGIFQVDGANYVKKLRQGYLESL
NPDYEDIHLDESNDIRTIGEVVSVYREK

Nucleotide


Download         Length: 807 bp        

>NTDB_id=1004142 E0F40_RS10295 WP_000090700.1 1899649..1900455(+) (irvR) [Streptococcus pneumoniae strain GPSC18 substr. ST13 isolate 55896440-41bd-11e5-998e-3c4a9275d6c6]
ATGGCAAGAGGACGAGGAAAATTAACTCCTCAAGATAAAGAGGATATGAAAGTCTTTTCCGCAAATCTTAACTCAATTTT
ATCTGATAGAAATTGTAAACAAGCTGAGCTATCTCGAGCGACAGGAATACCACCTAGCACATTGACAGGGTATGTAAAAG
GAACTTCTTTGCCAATCCCTGGCAATGTTCAAAAAATTGCAGATTTTTTTGGAGTACCTAAATCTGTATTAGACCCTAGA
TTTGTAACTAATAATTCTATGGTCGATGACTCTTCTTCTAATACTTCCTCTATCCAAACCATCTACGACCAACTAGAACC
GCCTAGACAGGGCAAAGTCCTGAATTATGCAAAGAGGCAACTGAAAGAGCAGAGGAACGAAGAAGAAACGAAGATAAACG
AAGTATCGGAGAACATCATCAGACTGGACGACTACAGACAGACTACTTACCGACGTGTTACTGGGGTTGTCTCTGCTGGT
AGTGGTTCGATACAGGACGACGATTTAGATATGGAGGTTTCGTTCTATGAGGATGAAATCCCAGACGACTACGACGCTAT
CGCTTATGTCGTCGGCAACTCTATGGAGCCAAAGATAAAGAATGGTGACTATCTTTTTATAAAGAATACCCAACAGGTTG
ATTATAACACTATCGGCATCTTCCAAGTAGACGGCGCTAACTATGTTAAGAAACTGCGTCAGGGATATCTGGAAAGCTTG
AATCCAGATTATGAGGATATACACCTAGACGAAAGCAACGACATCCGAACTATTGGGGAAGTTGTCAGTGTGTATAGAGA
GAAATAA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(30-74)

Peptidase S24-like (Peptidase_S24)

(155-262)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

38.944

100

0.44