Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   E0F40_RS00825 Genome accession   NZ_LR216065
Coordinates   147034..147474 (-) Length   146 a.a.
NCBI ID   WP_000861956.1    Uniprot ID   A0A0H2UNA2
Organism   Streptococcus pneumoniae strain GPSC18 substr. ST13 isolate 55896440-41bd-11e5-998e-3c4a9275d6c6     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 142034..152474
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F40_RS00795 (SAMEA3714487_00141) - 142295..143581 (+) 1287 WP_000278880.1 response regulator transcription factor -
  E0F40_RS00800 (SAMEA3714487_00142) - 143633..144166 (+) 534 WP_000729029.1 hypothetical protein -
  E0F40_RS00805 (SAMEA3714487_00143) nrdI 144244..144714 (+) 471 WP_000849621.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  E0F40_RS00815 (SAMEA3714487_00144) - 145007..146269 (-) 1263 WP_000075789.1 NRAMP family divalent metal transporter -
  E0F40_RS00820 (SAMEA3714487_00145) - 146579..147037 (-) 459 WP_000745054.1 DUF3021 domain-containing protein -
  E0F40_RS00825 (SAMEA3714487_00146) brsR 147034..147474 (-) 441 WP_000861956.1 LytTR family DNA-binding domain-containing protein Regulator
  E0F40_RS00835 (SAMEA3714487_00147) hexB 147831..149780 (+) 1950 WP_000018209.1 DNA mismatch repair endonuclease MutL Machinery gene
  E0F40_RS00840 (SAMEA3714487_00148) ruvA 149796..150389 (+) 594 WP_000273417.1 Holliday junction branch migration protein RuvA Machinery gene
  E0F40_RS00845 (SAMEA3714487_00149) - 150399..150584 (+) 186 Protein_160 DNA-3-methyladenine glycosylase I -
  E0F40_RS00855 (SAMEA3714487_00151) - 150772..151017 (+) 246 WP_001813542.1 hypothetical protein -
  E0F40_RS00860 (SAMEA3714487_00152) - 151014..151349 (+) 336 WP_000806926.1 hypothetical protein -
  E0F40_RS00865 (SAMEA3714487_00153) - 151362..151730 (+) 369 WP_000567222.1 hypothetical protein -
  E0F40_RS00870 (SAMEA3714487_00154) - 151717..152016 (+) 300 WP_001072467.1 DUF5960 family protein -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17183.84 Da        Isoelectric Point: 5.3783

>NTDB_id=1004050 E0F40_RS00825 WP_000861956.1 147034..147474(-) (brsR) [Streptococcus pneumoniae strain GPSC18 substr. ST13 isolate 55896440-41bd-11e5-998e-3c4a9275d6c6]
MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=1004050 E0F40_RS00825 WP_000861956.1 147034..147474(-) (brsR) [Streptococcus pneumoniae strain GPSC18 substr. ST13 isolate 55896440-41bd-11e5-998e-3c4a9275d6c6]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAAGAAACCGAAAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGAAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UNA2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363

Multiple sequence alignment