Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   E0F39_RS08525 Genome accession   NZ_LR216060
Coordinates   1586183..1586860 (-) Length   225 a.a.
NCBI ID   WP_001864885.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain GPSC47 substr. ST315     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1581183..1591860
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F39_RS08485 (SAMEA3713867_01610) - 1581344..1581973 (-) 630 WP_001864883.1 NAD(P)-dependent oxidoreductase -
  E0F39_RS08490 (SAMEA3713867_01611) - 1582212..1582412 (+) 201 WP_001826938.1 hypothetical protein -
  E0F39_RS08505 (SAMEA3713867_01612) - 1582843..1582983 (+) 141 WP_000422775.1 MazG-like protein -
  E0F39_RS08510 - 1582990..1583166 (+) 177 WP_000166031.1 MazG-like protein -
  E0F39_RS08515 (SAMEA3713867_01613) thrS 1583224..1585167 (+) 1944 WP_000608349.1 threonine--tRNA ligase -
  E0F39_RS08520 (SAMEA3713867_01614) - 1585216..1586190 (-) 975 WP_000887953.1 HAMP domain-containing histidine kinase -
  E0F39_RS08525 (SAMEA3713867_01615) braR 1586183..1586860 (-) 678 WP_001864885.1 response regulator transcription factor Regulator
  E0F39_RS08530 (SAMEA3713867_01616) - 1587016..1588089 (+) 1074 WP_001273825.1 DUF2974 domain-containing protein -
  E0F39_RS08535 (SAMEA3713867_01617) - 1588180..1588482 (-) 303 WP_000281594.1 hypothetical protein -
  E0F39_RS08540 (SAMEA3713867_01618) - 1588551..1588988 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  E0F39_RS08545 (SAMEA3713867_01619) - 1589064..1589906 (-) 843 WP_000160943.1 metallophosphoesterase family protein -
  E0F39_RS08550 (SAMEA3713867_01620) - 1590018..1590668 (+) 651 WP_000188505.1 metal-dependent transcriptional regulator -
  E0F39_RS08560 (SAMEA3713867_01621) - 1590858..1591523 (+) 666 WP_029749143.1 nicotinamide mononucleotide transporter -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25883.06 Da        Isoelectric Point: 4.9731

>NTDB_id=1003872 E0F39_RS08525 WP_001864885.1 1586183..1586860(-) (braR) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVACLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=1003872 E0F39_RS08525 WP_001864885.1 1586183..1586860(-) (braR) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
ATGCACAAGATTTTATTAGTGGAAGATGATCAGGTCATTCGTCAACAGGTCGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCCAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTTTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTTGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

34.894

100

0.364