Detailed information NTG1003632

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: EL305_RS02925
• Genome accession: NZ_LR134528
• Coordinates: 501235..503514 (-)
• Length: 759 a.a.
• NCBI ID: WP_002236866.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain NCTC12163
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 496235..508514

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL305_RS02905 (NCTC12163_00502)	-	496792..498012 (+)	1221	WP_002236862.1	restriction endonuclease subunit S	-
EL305_RS13935	-	498091..501188 (+)	3098	Protein_495	HsdR family type I site-specific deoxyribonuclease	-
EL305_RS02925 (NCTC12163_00506)	clpC	501235..503514 (-)	2280	WP_002236866.1	ATP-dependent Clp protease ATP-binding subunit ClpA	Regulator
EL305_RS02930 (NCTC12163_00507)	clpS	503516..503818 (-)	303	WP_002221161.1	ATP-dependent Clp protease adapter ClpS	-
EL305_RS02935	-	504061..504264 (+)	204	WP_002217533.1	cold-shock protein	-
EL305_RS02940 (NCTC12163_00509)	pmbA	504561..505892 (-)	1332	WP_002236867.1	metalloprotease PmbA	-
EL305_RS14230	-	505882..506013 (+)	132	WP_255304551.1	hypothetical protein	-
EL305_RS02945 (NCTC12163_00510)	yjgA	506045..506551 (+)	507	WP_002225402.1	ribosome biogenesis factor YjgA	-
EL305_RS02950 (NCTC12163_00511)	-	506598..507311 (+)	714	WP_002236868.1	hypothetical protein	-

Sequence

Protein

• Length: 759 a.a.
• Molecular weight: 83867.75 Da
• Isoelectric Point: 6.9734

>NTDB_id=1003632 EL305_RS02925 WP_002236866.1 501235..503514(-) (clpC) [Neisseria meningitidis strain NCTC12163]
MLAPELEQILQQLYREARKAHYEFISLEHLLLVLIEEDASVPNVLKLCGADLKVVSEQLAASVAENTPLIPEHLLDTVET
RPTLGFQRVMQRAMVHTQSAGKAAVEPLDVLVALMSETDSHTVYFLKLQSVTRFEVLRCIAHGSPDDEDGNDSDGLGREG
EEAEQKTGSLSDYTVNLNTEVKAGRIDPLIGRKHEMERLVQILCRRRKNNPLLVGEAGVGKTALAEGLAHQIVNGGIPDA
LKDAEVYALDMGSLLAGTKYRGDFEARVKSVLKQLEKIPHAILFIDEIHTIIGAGSTSGGTMDASNLLKPALAKGSLRCI
GATTYDEYRTIFDKDYALSRRFQKIDVVEPTVSETVQILRGLKPMFEAFHQVRYTQGALEAAAELSARYINERFLPDKAI
DVMDEAGAAQRILPKSKQKKVIGKAQIETVIAKVARIPEKTVSHDDKQVLQFLGRDLKNMVYGQENAIDALVAAVKMSRS
GLGLPDKPIGSFLFSGPTGVGKTEAAKQLAYSMGVPLQRFDMSEYMERHAVSRLIGAPPGYVGFEQGGLLTEAVNKQPHC
VLLLDEIEKAHPDIFNVLLQVMDAGKLTDNNGKSADFRNVILIMTTNAGAESLSRPGLGFTAKRERGDEMQAINKLFTPE
FRNRLDAIIPFAPLSEPIIAKVVDKFLLRLEHRLLDKKVEAEFTPALRKYLARKGFDPQMGARPMHRLIQEKIRKPLADE
LLFGKLSNGGFVRIDWDAAKEEAVLKFKKSKVKPETETV

Nucleotide

• Length: 2280 bp

>NTDB_id=1003632 EL305_RS02925 WP_002236866.1 501235..503514(-) (clpC) [Neisseria meningitidis strain NCTC12163]
ATGCTTGCACCCGAATTGGAACAGATTTTGCAGCAGCTTTACCGCGAGGCGCGTAAGGCTCATTATGAATTTATCAGCCT
CGAGCATCTGCTTTTGGTACTCATCGAAGAAGATGCCTCCGTGCCGAACGTCTTAAAACTATGCGGCGCGGATTTGAAAG
TGGTGTCCGAACAGCTCGCCGCCAGCGTTGCCGAAAACACCCCCCTGATTCCCGAACACCTTTTAGACACGGTCGAAACC
CGGCCCACGCTCGGCTTCCAACGCGTGATGCAACGGGCGATGGTGCATACCCAGTCTGCCGGAAAAGCCGCAGTCGAACC
GTTGGACGTTTTGGTCGCGCTGATGAGCGAAACCGACAGCCACACCGTCTATTTCCTCAAGCTGCAATCGGTTACGCGTT
TTGAAGTTTTGCGCTGTATTGCCCATGGCTCGCCCGATGACGAGGATGGCAATGATTCAGACGGCCTGGGACGCGAGGGC
GAAGAAGCGGAACAAAAAACCGGCTCCCTTTCCGACTACACCGTCAACCTCAACACCGAAGTCAAAGCCGGCCGTATCGA
CCCTTTGATTGGTCGCAAACACGAAATGGAACGGCTGGTGCAAATCCTATGCCGCCGCCGCAAAAACAATCCGCTTTTGG
TCGGCGAAGCAGGCGTGGGCAAAACCGCGCTGGCGGAAGGTTTGGCACATCAAATCGTCAACGGCGGCATTCCAGACGCG
CTTAAAGATGCCGAAGTGTACGCGCTGGATATGGGCTCGCTGTTGGCGGGCACGAAATACCGTGGCGACTTTGAAGCGCG
GGTCAAATCCGTCTTGAAACAGCTCGAAAAAATCCCGCACGCCATTTTGTTTATCGACGAAATCCACACCATCATCGGCG
CAGGCAGCACCAGCGGCGGCACCATGGACGCGTCCAACCTGCTCAAACCCGCGCTGGCAAAAGGTTCGCTGCGCTGCATC
GGCGCAACCACCTACGACGAATACCGCACCATTTTCGACAAAGACTATGCCTTAAGCCGCCGCTTCCAAAAAATCGACGT
GGTCGAACCCACCGTTTCCGAAACCGTACAAATCCTGCGCGGCTTGAAGCCGATGTTTGAAGCCTTCCACCAAGTCCGCT
ATACGCAAGGCGCACTCGAAGCCGCCGCCGAACTCTCCGCACGCTACATCAACGAGCGTTTCCTGCCCGACAAAGCCATC
GACGTGATGGACGAAGCAGGCGCGGCGCAACGGATTCTGCCCAAATCCAAACAGAAAAAAGTCATCGGCAAAGCGCAAAT
CGAAACCGTCATCGCCAAAGTCGCGCGGATTCCAGAAAAAACCGTGTCGCACGACGACAAACAGGTGCTGCAATTCCTCG
GCCGCGATTTGAAAAACATGGTTTACGGTCAAGAAAACGCCATCGACGCGCTGGTTGCCGCCGTCAAAATGTCGCGTTCG
GGCTTGGGACTGCCCGACAAACCGATAGGCAGCTTCCTCTTCTCCGGCCCGACCGGCGTGGGCAAAACCGAAGCCGCCAA
ACAGCTTGCCTACTCGATGGGCGTACCGCTGCAACGCTTTGATATGTCCGAATACATGGAACGCCATGCCGTATCGCGCC
TCATCGGCGCGCCTCCGGGCTACGTCGGCTTCGAACAAGGCGGCCTTTTGACCGAAGCCGTCAACAAACAGCCGCATTGC
GTGTTGCTCTTGGACGAAATCGAAAAAGCCCACCCCGACATTTTCAACGTCCTCCTGCAAGTCATGGACGCAGGCAAACT
GACCGACAACAACGGCAAGAGTGCCGATTTCCGCAACGTCATCCTGATTATGACCACCAACGCGGGCGCGGAAAGCCTCA
GCCGCCCCGGCCTCGGCTTTACCGCCAAGCGCGAACGCGGCGACGAAATGCAGGCCATCAACAAACTCTTCACGCCCGAG
TTCCGCAACCGCTTGGACGCGATTATCCCGTTTGCACCCCTGTCCGAACCCATTATCGCCAAAGTCGTGGACAAATTCCT
GCTCCGGCTCGAACACCGGCTCCTCGACAAGAAAGTCGAAGCCGAATTCACACCGGCATTGCGCAAATATCTGGCGAGAA
AAGGTTTCGACCCGCAAATGGGCGCGCGCCCGATGCACCGCCTGATTCAGGAAAAAATCCGCAAACCGCTCGCCGACGAA
CTCCTGTTCGGCAAACTATCCAACGGCGGCTTCGTGCGGATAGACTGGGATGCGGCAAAAGAAGAAGCCGTGTTGAAATT
TAAGAAAAGCAAGGTTAAACCTGAAACAGAAACTGTTTAA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (212-343)

• AAA lid domain (AAA_lid_9) (352-448)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (654-734)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-61)

• AAA domain (Cdc48 subfamily) (AAA_2) (487-648)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	37.871	100	0.403
clpC	Bacillus subtilis subsp. subtilis str. 168	37.282	100	0.394
clpA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	41.678	94.203	0.393
clpC	Streptococcus thermophilus LMG 18311	44.968	81.159	0.365
clpC	Streptococcus thermophilus LMD-9	44.805	81.159	0.364