Detailed information NTG1003510

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: EL297_RS06725
• Genome accession: NZ_LR134525
• Coordinates: 1125767..1128046 (+)
• Length: 759 a.a.
• NCBI ID: WP_002236866.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain NCTC10025
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1120767..1133046

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL297_RS06695 (NCTC10025_01110)	-	1121962..1122675 (-)	714	WP_002246107.1	hypothetical protein	-
EL297_RS06700 (NCTC10025_01111)	yjgA	1122722..1123234 (-)	513	WP_002246106.1	ribosome biogenesis factor YjgA	-
EL297_RS06705 (NCTC10025_01112)	pmbA	1123388..1124719 (+)	1332	WP_002246105.1	metalloprotease PmbA	-
EL297_RS06715	-	1125017..1125220 (-)	204	WP_002217533.1	cold-shock protein	-
EL297_RS06720 (NCTC10025_01114)	clpS	1125463..1125765 (+)	303	WP_002221161.1	ATP-dependent Clp protease adapter ClpS	-
EL297_RS06725 (NCTC10025_01115)	clpC	1125767..1128046 (+)	2280	WP_002236866.1	ATP-dependent Clp protease ATP-binding subunit ClpA	Regulator
EL297_RS13710	-	1128093..1131190 (-)	3098	Protein_1106	HsdR family type I site-specific deoxyribonuclease	-
EL297_RS06745 (NCTC10025_01119)	-	1131269..1131841 (-)	573	WP_232012966.1	restriction endonuclease subunit S	-
EL297_RS06750 (NCTC10025_01120)	-	1131895..1132488 (-)	594	WP_002213928.1	restriction endonuclease subunit S	-

Sequence

Protein

• Length: 759 a.a.
• Molecular weight: 83867.75 Da
• Isoelectric Point: 6.9734

>NTDB_id=1003510 EL297_RS06725 WP_002236866.1 1125767..1128046(+) (clpC) [Neisseria meningitidis strain NCTC10025]
MLAPELEQILQQLYREARKAHYEFISLEHLLLVLIEEDASVPNVLKLCGADLKVVSEQLAASVAENTPLIPEHLLDTVET
RPTLGFQRVMQRAMVHTQSAGKAAVEPLDVLVALMSETDSHTVYFLKLQSVTRFEVLRCIAHGSPDDEDGNDSDGLGREG
EEAEQKTGSLSDYTVNLNTEVKAGRIDPLIGRKHEMERLVQILCRRRKNNPLLVGEAGVGKTALAEGLAHQIVNGGIPDA
LKDAEVYALDMGSLLAGTKYRGDFEARVKSVLKQLEKIPHAILFIDEIHTIIGAGSTSGGTMDASNLLKPALAKGSLRCI
GATTYDEYRTIFDKDYALSRRFQKIDVVEPTVSETVQILRGLKPMFEAFHQVRYTQGALEAAAELSARYINERFLPDKAI
DVMDEAGAAQRILPKSKQKKVIGKAQIETVIAKVARIPEKTVSHDDKQVLQFLGRDLKNMVYGQENAIDALVAAVKMSRS
GLGLPDKPIGSFLFSGPTGVGKTEAAKQLAYSMGVPLQRFDMSEYMERHAVSRLIGAPPGYVGFEQGGLLTEAVNKQPHC
VLLLDEIEKAHPDIFNVLLQVMDAGKLTDNNGKSADFRNVILIMTTNAGAESLSRPGLGFTAKRERGDEMQAINKLFTPE
FRNRLDAIIPFAPLSEPIIAKVVDKFLLRLEHRLLDKKVEAEFTPALRKYLARKGFDPQMGARPMHRLIQEKIRKPLADE
LLFGKLSNGGFVRIDWDAAKEEAVLKFKKSKVKPETETV

Nucleotide

• Length: 2280 bp

>NTDB_id=1003510 EL297_RS06725 WP_002236866.1 1125767..1128046(+) (clpC) [Neisseria meningitidis strain NCTC10025]
ATGCTTGCACCCGAATTGGAACAGATTTTGCAGCAGCTTTACCGCGAGGCGCGTAAGGCTCATTATGAATTTATCAGCCT
CGAGCATCTGCTTTTGGTACTCATCGAAGAAGATGCCTCCGTGCCGAACGTCTTAAAACTATGCGGCGCGGATTTGAAAG
TGGTGTCCGAACAGCTCGCCGCCAGCGTTGCCGAAAACACCCCCCTGATTCCCGAACACCTTTTAGACACGGTCGAAACC
CGGCCCACGCTCGGCTTCCAACGCGTGATGCAACGGGCGATGGTGCATACCCAGTCTGCCGGAAAAGCCGCAGTCGAACC
GTTGGACGTTTTGGTCGCGCTGATGAGCGAAACCGACAGCCACACCGTCTATTTCCTCAAGCTGCAATCGGTTACGCGTT
TTGAAGTTTTGCGCTGTATTGCCCATGGCTCGCCCGATGACGAGGATGGCAATGATTCAGACGGCCTGGGACGCGAGGGC
GAAGAAGCGGAACAAAAAACCGGCTCCCTTTCCGACTACACCGTCAACCTCAACACCGAAGTCAAAGCCGGCCGTATCGA
CCCTTTGATTGGTCGCAAACACGAAATGGAACGGCTGGTGCAAATCCTATGCCGCCGCCGCAAAAACAATCCGCTTTTGG
TCGGCGAAGCAGGCGTGGGCAAAACCGCGCTGGCGGAAGGTTTGGCACATCAAATCGTCAACGGCGGCATTCCAGACGCG
CTTAAAGATGCCGAAGTGTACGCGCTGGATATGGGCTCGCTGTTGGCGGGCACGAAATACCGTGGCGACTTTGAAGCGCG
GGTCAAATCCGTCTTGAAACAGCTCGAAAAAATCCCGCACGCCATTTTGTTTATCGACGAAATCCACACCATCATCGGCG
CAGGCAGCACCAGCGGCGGCACCATGGACGCGTCCAACCTGCTCAAACCCGCGCTGGCAAAAGGTTCGCTGCGCTGCATC
GGCGCAACCACCTACGACGAATACCGCACCATTTTCGACAAAGACTATGCCTTAAGCCGCCGCTTCCAAAAAATCGACGT
GGTCGAACCCACCGTTTCCGAAACCGTACAAATCCTGCGCGGCTTGAAGCCGATGTTTGAAGCCTTCCACCAAGTCCGCT
ATACGCAAGGCGCACTCGAAGCCGCCGCCGAACTCTCCGCACGCTACATCAACGAGCGTTTCCTGCCCGACAAAGCCATC
GACGTGATGGACGAAGCAGGCGCGGCGCAACGGATTCTGCCCAAATCCAAACAGAAAAAAGTCATCGGCAAAGCGCAAAT
CGAAACCGTCATCGCCAAAGTCGCGCGGATTCCAGAAAAAACCGTGTCGCACGACGACAAACAGGTGCTGCAATTCCTCG
GCCGCGATTTGAAAAACATGGTTTACGGTCAAGAAAACGCCATCGACGCGCTGGTTGCCGCCGTCAAAATGTCGCGTTCG
GGCTTGGGACTGCCCGACAAACCGATAGGCAGCTTCCTCTTCTCCGGCCCGACCGGCGTGGGCAAAACCGAAGCCGCCAA
ACAGCTTGCCTACTCGATGGGCGTACCGCTGCAACGCTTTGATATGTCCGAATACATGGAACGCCATGCCGTATCGCGCC
TCATCGGCGCGCCTCCGGGCTACGTCGGCTTCGAACAAGGCGGCCTTTTGACCGAAGCCGTCAACAAACAGCCGCATTGC
GTGTTGCTCTTGGACGAAATCGAAAAAGCCCACCCCGACATTTTCAACGTCCTCCTGCAAGTCATGGACGCAGGCAAACT
GACCGACAACAACGGCAAGAGTGCCGATTTCCGCAACGTCATCCTGATTATGACCACCAACGCGGGCGCGGAAAGCCTCA
GCCGCCCCGGCCTCGGCTTTACCGCCAAGCGCGAACGCGGCGACGAAATGCAGGCCATCAACAAACTCTTCACGCCCGAG
TTCCGCAACCGCTTGGACGCGATTATCCCGTTTGCACCCCTGTCCGAACCCATTATCGCCAAAGTCGTGGACAAATTCCT
GCTCCGGCTCGAACACCGGCTCCTCGACAAGAAAGTCGAAGCCGAATTCACACCGGCATTGCGCAAATATCTGGCGAGAA
AAGGTTTCGACCCGCAAATGGGCGCGCGCCCGATGCACCGCCTGATTCAGGAAAAAATCCGCAAACCGCTCGCCGACGAA
CTCCTGTTCGGCAAACTATCCAACGGCGGCTTCGTGCGGATAGACTGGGATGCGGCAAAAGAAGAAGCCGTGTTGAAATT
TAAGAAAAGCAAGGTTAAACCTGAAACAGAAACTGTTTAA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (212-343)

• AAA lid domain (AAA_lid_9) (352-448)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (654-734)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-61)

• AAA domain (Cdc48 subfamily) (AAA_2) (487-648)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	37.871	100	0.403
clpC	Bacillus subtilis subsp. subtilis str. 168	37.282	100	0.394
clpA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	41.678	94.203	0.393
clpC	Streptococcus thermophilus LMG 18311	44.968	81.159	0.365
clpC	Streptococcus thermophilus LMD-9	44.805	81.159	0.364