NTDB

Overview

Name	pilD	Type	Machinery gene
Locus tag	EL310_RS09225	Genome accession	NZ_LR134522
Coordinates	1576136..1576996 (+)	Length	286 a.a.
NCBI ID	WP_002220276.1	Uniprot ID	-
Organism	Neisseria meningitidis strain NCTC3372
Function	assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1571136..1581996

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL310_RS09205 (NCTC3372_01555)	dapD	1571842..1572663 (-)	822	WP_002216408.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
EL310_RS09215 (NCTC3372_01556)	pgi	1572830..1574473 (-)	1644	WP_002245857.1	glucose-6-phosphate isomerase	-
EL310_RS09220 (NCTC3372_01557)	pilG	1574830..1576062 (+)	1233	WP_002216405.1	type 4 pilus assembly protein PilG	Machinery gene
EL310_RS09225 (NCTC3372_01558)	pilD	1576136..1576996 (+)	861	WP_002220276.1	prepilin peptidase	Machinery gene
EL310_RS09230 (NCTC3372_01559)	coaE	1576998..1577630 (+)	633	WP_002221968.1	dephospho-CoA kinase	-
EL310_RS09235 (NCTC3372_01560)	-	1577623..1577832 (+)	210	WP_002212333.1	DNA gyrase inhibitor YacG	-
EL310_RS09240 (NCTC3372_01561)	pilB	1577917..1579594 (-)	1678	Protein_1541	type IV-A pilus assembly ATPase PilB	-
EL310_RS09255 (NCTC3372_01564)	-	1580036..1580482 (-)	447	WP_002233503.1	DUF441 domain-containing protein	-
EL310_RS09260 (NCTC3372_01565)	ispB	1580487..1581461 (-)	975	WP_002216396.1	octaprenyl diphosphate synthase	-
EL310_RS09270 (NCTC3372_01566)	rplU	1581685..1581993 (+)	309	WP_002216394.1	50S ribosomal protein L21	-

Sequence

Protein

Download Length: 286 a.a. Molecular weight: 31359.40 Da Isoelectric Point: 8.2213

                                >NTDB_id=1003455 EL310_RS09225 WP_002220276.1 1576136..1576996(+) (pilD) [Neisseria meningitidis strain NCTC3372]

MSDLSVLSPFAVPLAAVFGLLVGSFLNVVIYRVPVMMERGWTVFAKEYLNLPLTEEESRTFNLMKPDSCCPKCRVPIRAW

QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP

LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSIWLLCAVYKLIKGEIGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV

AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide

Download Length: 861 bp

                                >NTDB_id=1003455 EL310_RS09225 WP_002220276.1 1576136..1576996(+) (pilD) [Neisseria meningitidis strain NCTC3372]

ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCGGTGTTCGGGCTGCTGGTCGGAAGTTTCTTAAA

TGTCGTCATTTACCGCGTGCCGGTCATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAATATTTAAACCTGCCGCTGA

CCGAAGAGGAAAGCCGTACCTTCAACCTGATGAAACCGGATTCCTGCTGTCCCAAATGTCGCGTGCCGATACGCGCGTGG

CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC

CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTTGCCTGGCAATACGGCTGGTCTTGGATTACATTGGGCGGTT

TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACCTTACCC

TTGATTTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG

CTATGGTTCGATATGGCTTTTATGCGCGGTATATAAACTGATTAAAGGCGAAATCGGTATGGGCAACGGAGATTTCAAAC

TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC

GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT

TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(17-124)

Type IV leader peptidase family (Peptidase_A24)

(134-242)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
pilD	Neisseria gonorrhoeae MS11	96.14	99.65	0.958
pilD	Vibrio cholerae strain A1552	44.444	100	0.448
pilD	Vibrio campbellii strain DS40M4	44.928	96.503	0.434
pilD	Acinetobacter baumannii D1279779	46.97	92.308	0.434
pilD	Acinetobacter nosocomialis M2	46.97	92.308	0.434

Detailed information NTG1003455