Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   QQE12_RS07885 Genome accession   NZ_CP156695
Coordinates   1637144..1638118 (-) Length   324 a.a.
NCBI ID   WP_000697220.1    Uniprot ID   W8U5L8
Organism   Staphylococcus aureus strain SA-684     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1632144..1643118
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QQE12_RS07845 (QQE12_007845) gcvT 1632645..1633736 (-) 1092 WP_285238825.1 glycine cleavage system aminomethyltransferase GcvT -
  QQE12_RS07850 (QQE12_007850) - 1633895..1634419 (-) 525 WP_001015125.1 shikimate kinase -
  QQE12_RS07855 (QQE12_007855) - 1634409..1634555 (-) 147 WP_001789879.1 hypothetical protein -
  QQE12_RS07860 (QQE12_007860) comGF 1634652..1635149 (-) 498 WP_001794328.1 competence type IV pilus minor pilin ComGF Machinery gene
  QQE12_RS07865 (QQE12_007865) comGE 1635067..1635366 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  QQE12_RS07870 (QQE12_007870) comGD 1635353..1635799 (-) 447 WP_001791207.1 competence type IV pilus minor pilin ComGD Machinery gene
  QQE12_RS07875 (QQE12_007875) comGC 1635777..1636088 (-) 312 WP_000472257.1 competence type IV pilus major pilin ComGC Machinery gene
  QQE12_RS07880 (QQE12_007880) comGB 1636102..1637172 (-) 1071 WP_000776412.1 competence type IV pilus assembly protein ComGB Machinery gene
  QQE12_RS07885 (QQE12_007885) comGA 1637144..1638118 (-) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  QQE12_RS07890 (QQE12_007890) - 1638170..1638793 (-) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  QQE12_RS07895 (QQE12_007895) - 1638790..1639119 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  QQE12_RS07900 (QQE12_007900) - 1639119..1640105 (-) 987 WP_000161314.1 ROK family glucokinase -
  QQE12_RS07905 (QQE12_007905) - 1640102..1640305 (-) 204 WP_000087561.1 YqgQ family protein -
  QQE12_RS07910 (QQE12_007910) - 1640286..1641749 (-) 1464 WP_001017867.1 rhomboid family intramembrane serine protease -
  QQE12_RS07915 (QQE12_007915) - 1641761..1642300 (-) 540 WP_000164553.1 5-formyltetrahydrofolate cyclo-ligase -
  QQE12_RS07920 (QQE12_007920) rpmG 1642509..1642658 (-) 150 WP_001265709.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36897.96 Da        Isoelectric Point: 8.8516

>NTDB_id=1002251 QQE12_RS07885 WP_000697220.1 1637144..1638118(-) (comGA) [Staphylococcus aureus strain SA-684]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=1002251 QQE12_RS07885 WP_000697220.1 1637144..1638118(-) (comGA) [Staphylococcus aureus strain SA-684]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATCGTGCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8U5L8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

100

100

1
  comGA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment