Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   EL147_RS08180 Genome accession   NZ_LR134341
Coordinates   1672971..1673612 (+) Length   213 a.a.
NCBI ID   WP_007892962.1    Uniprot ID   G5K813
Organism   Streptococcus pseudoporcinus strain NCTC13786     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1667971..1678612
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL147_RS08160 (NCTC13786_01640) - 1668503..1669243 (+) 741 WP_007892963.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  EL147_RS08165 (NCTC13786_01641) pknB 1669240..1671168 (+) 1929 WP_007892968.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  EL147_RS08170 (NCTC13786_01642) liaF 1671282..1671977 (+) 696 WP_007892966.1 cell wall-active antibiotics response protein LiaF -
  EL147_RS08175 (NCTC13786_01643) - 1671974..1672978 (+) 1005 WP_007896177.1 sensor histidine kinase -
  EL147_RS08180 (NCTC13786_01644) vraR 1672971..1673612 (+) 642 WP_007892962.1 response regulator transcription factor Regulator
  EL147_RS08185 (NCTC13786_01645) - 1673646..1675046 (+) 1401 WP_007892964.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  EL147_RS08190 (NCTC13786_01646) - 1675046..1675399 (+) 354 WP_007892969.1 S1 RNA-binding domain-containing protein -
  EL147_RS08195 (NCTC13786_01647) tnpA 1675587..1676042 (+) 456 WP_007896184.1 IS200/IS605 family transposase -
  EL147_RS08200 (NCTC13786_01648) cysK 1676108..1677073 (-) 966 WP_007891534.1 cysteine synthase A -
  EL147_RS08205 (NCTC13786_01649) - 1677186..1677815 (-) 630 WP_007891527.1 YigZ family protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23961.62 Da        Isoelectric Point: 4.9960

>NTDB_id=1002132 EL147_RS08180 WP_007892962.1 1672971..1673612(+) (vraR) [Streptococcus pseudoporcinus strain NCTC13786]
MDNIKVILVDDHEMVRLGLKSFLNMQKDITVVAEASNGRQGVKLALEIQPDVVVMDLVMPELDGVEATLEILQKWSEAKI
LVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIRKVAKGQLAIETEVDKKIKAHNQHPDLHEELTAREYDILYLLA
KGYDNQTIADELFISLKTVKTHVSNILSKLEVDDRTQAVVYAFRHHLVPQDDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=1002132 EL147_RS08180 WP_007892962.1 1672971..1673612(+) (vraR) [Streptococcus pseudoporcinus strain NCTC13786]
ATGGATAATATTAAGGTAATTTTAGTTGATGATCATGAAATGGTGCGTTTAGGATTAAAAAGTTTTTTAAATATGCAAAA
AGACATCACTGTGGTTGCCGAAGCTTCAAATGGACGACAAGGGGTTAAGCTGGCACTTGAGATACAACCTGATGTGGTGG
TGATGGACCTTGTCATGCCAGAATTAGACGGAGTGGAAGCTACACTTGAAATTTTACAGAAATGGTCAGAAGCTAAGATT
TTGGTACTGACATCTTATTTAGATAATGAAAAAATCTATCCTGTTATTGAAGCAGGAGCAAAAGGTTACATGCTAAAGAC
TTCAAGTGCTGCTGAAATACTCAATGCCATTCGTAAAGTGGCTAAAGGACAGTTGGCAATTGAAACAGAAGTTGATAAAA
AGATTAAAGCTCATAATCAACATCCTGACTTACATGAGGAATTGACAGCACGTGAATACGATATCTTATACCTTTTAGCT
AAGGGTTATGACAATCAAACCATTGCAGATGAACTCTTCATATCCTTGAAGACAGTTAAGACCCATGTGTCCAATATTTT
ATCTAAGCTTGAAGTTGATGATCGGACGCAAGCAGTAGTCTACGCTTTCCGACACCACTTAGTGCCACAAGACGACAATT
AG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5K813

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.242

97.183

0.488
  degU Bacillus subtilis subsp. subtilis str. 168

36.283

100

0.385

Multiple sequence alignment