Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   EL147_RS06330 Genome accession   NZ_LR134341
Coordinates   1292948..1294915 (+) Length   655 a.a.
NCBI ID   WP_007893835.1    Uniprot ID   G5K7I0
Organism   Streptococcus pseudoporcinus strain NCTC13786     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1287948..1299915
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL147_RS06320 - 1291736..1291915 (-) 180 WP_007893796.1 peptidase -
  EL147_RS06325 (NCTC13786_01265) - 1291900..1292799 (-) 900 WP_232010993.1 hypothetical protein -
  EL147_RS06330 (NCTC13786_01266) hexB 1292948..1294915 (+) 1968 WP_007893835.1 DNA mismatch repair endonuclease MutL Machinery gene
  EL147_RS06335 (NCTC13786_01267) - 1294926..1296149 (+) 1224 WP_007893804.1 MFS transporter -
  EL147_RS06340 (NCTC13786_01268) ruvA 1296151..1296744 (+) 594 WP_007893783.1 Holliday junction branch migration protein RuvA Machinery gene
  EL147_RS06345 (NCTC13786_01269) - 1296751..1297305 (+) 555 WP_007893754.1 DNA-3-methyladenine glycosylase I -
  EL147_RS06350 (NCTC13786_01270) cinA 1297421..1298680 (+) 1260 WP_007893844.1 competence/damage-inducible protein A Machinery gene
  EL147_RS06355 (NCTC13786_01271) recA 1298770..1299912 (+) 1143 WP_007893872.1 recombinase RecA Machinery gene

Sequence

Protein


Download         Length: 655 a.a.        Molecular weight: 73897.39 Da        Isoelectric Point: 5.3658

>NTDB_id=1002108 EL147_RS06330 WP_007893835.1 1292948..1294915(+) (hexB) [Streptococcus pseudoporcinus strain NCTC13786]
MTKIIELPEILANQIAAGEVIERPASVVKELVENAIDAKSSQITIDIEESGLKSITITDNGEGMSEQDLPMSILRHATSK
IKNQGDLFRIRTLGFRGEALPSIASISELTIASATEESEHGSQLFVRGGKIEGQEAISMPVGTRIRVENLFYNTPARLKY
MKSLQSELAHIVDVVNRLSLGHPEIAFTLISDGREMTRTSGSGQLKQAIAGIYGLKTAKKMIEIANADLDFDVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALIST
AIAESLKAQDLIPDALENLAKSSTRSLPKAEQTRLPLQTRKLYYDPHENDFFVEKKDVSEAQTPIYSDSFDLDRPVKLAE
EASVELSSPAVKHASRPDTEELVGDHSDLTFKNKHKLEQVVERLENEEASTFPELDYFGQMHGTYLFAQGVDGLFIIDQH
AAQERVKYEYYREKIGEVDSSLQQLLVPYLFEFSGSDFLTLQEKMSLLNDVGIYLEPYGHHTFILREHPIWMKESEIEAG
VYEMCDMLLLTQEVSIKTYRAELAIMMSCKKSIKANHTLDDYSARQLLLQLAQCKNPYNCPHGRPVLIHFSKSDMEKMFR
RIQENHTSLRDLGKY

Nucleotide


Download         Length: 1968 bp        

>NTDB_id=1002108 EL147_RS06330 WP_007893835.1 1292948..1294915(+) (hexB) [Streptococcus pseudoporcinus strain NCTC13786]
ATGACTAAAATTATTGAATTACCAGAAATTCTCGCCAATCAGATTGCAGCTGGGGAAGTTATTGAGCGTCCAGCAAGTGT
CGTTAAAGAATTGGTAGAGAATGCCATTGATGCAAAAAGTAGTCAGATTACTATTGATATTGAAGAATCAGGCTTAAAGT
CTATAACCATAACCGATAATGGTGAAGGCATGTCGGAGCAAGATTTGCCCATGAGTATCCTTCGTCATGCAACTAGTAAG
ATAAAAAATCAGGGTGATCTTTTTCGTATTAGAACACTTGGTTTTAGAGGAGAGGCATTACCTTCGATTGCTTCAATTAG
TGAGTTGACCATTGCTTCCGCTACAGAAGAGTCTGAGCATGGTAGCCAACTCTTTGTGCGTGGTGGCAAGATTGAGGGGC
AAGAAGCAATTTCGATGCCTGTTGGAACTCGGATAAGGGTTGAAAATCTTTTTTATAATACGCCAGCACGTCTAAAATAC
ATGAAGAGTCTCCAATCAGAATTGGCTCATATTGTCGATGTGGTCAATCGTTTAAGTTTAGGACACCCTGAAATAGCCTT
CACTCTCATATCTGATGGGCGAGAAATGACTAGAACATCTGGAAGTGGTCAGTTGAAACAAGCCATTGCAGGTATTTACG
GTCTAAAAACTGCAAAAAAAATGATCGAAATAGCTAATGCAGACTTAGACTTTGACGTCAGTGGTTATGTTAGTCTGCCA
GAACTAACTCGGGCAAACCGAAATTATATTACCATTTTAATTAATGGTCGCTATATCAAAAATTTTTTACTCAATCGTGC
TATTTTAGATGGCTATGGTTCCAAATTAATGGTGGGGCGTTTCCCGATTGTGGTTATTGATATTCAGATTGACCCTTACT
TAGCGGATGTCAACGTTCACCCGACAAAGCAAGAAGTTCGTATCTCTAAGGAAAGAGAGTTAATGGCTTTGATTAGCACT
GCTATTGCAGAAAGTTTAAAAGCCCAAGATTTAATTCCTGATGCCTTGGAAAATTTAGCAAAATCAAGCACTCGTTCTTT
GCCAAAAGCAGAGCAGACGCGTTTGCCTTTACAGACTCGTAAACTTTATTATGATCCCCACGAAAATGATTTTTTTGTCG
AAAAGAAGGATGTTAGCGAAGCTCAGACTCCGATTTATTCTGACAGCTTTGATCTTGACAGACCTGTCAAGCTAGCAGAA
GAGGCATCAGTGGAATTATCATCGCCTGCTGTTAAGCATGCTAGTCGCCCAGATACTGAAGAGCTAGTAGGTGATCATTC
TGACTTAACTTTTAAAAATAAGCATAAGTTGGAACAAGTGGTGGAACGTTTGGAAAACGAAGAAGCGTCGACATTTCCAG
AGTTAGACTATTTTGGACAAATGCACGGGACTTATCTCTTTGCTCAAGGGGTTGATGGGCTTTTCATTATTGATCAGCAT
GCGGCTCAGGAGCGGGTTAAGTATGAATATTACCGTGAGAAAATTGGGGAAGTTGACAGCAGTTTACAGCAATTGCTTGT
TCCCTATCTTTTTGAATTTTCAGGCTCTGATTTTTTGACTTTACAGGAAAAGATGTCTCTTTTAAATGATGTGGGAATCT
ATCTGGAGCCGTACGGACATCATACTTTTATTTTGCGGGAACACCCTATTTGGATGAAAGAAAGTGAGATTGAAGCTGGC
GTTTATGAGATGTGTGATATGTTGCTTTTGACTCAGGAAGTTTCCATTAAGACCTACAGGGCTGAGTTGGCTATCATGAT
GAGCTGTAAAAAATCAATCAAAGCTAATCATACCTTGGATGATTATTCTGCAAGACAATTGTTGTTACAGTTGGCACAGT
GTAAAAATCCTTATAATTGTCCACATGGGCGTCCAGTCTTGATTCATTTTAGTAAATCAGATATGGAAAAAATGTTCCGC
CGTATTCAAGAAAATCATACTAGTTTGAGAGATTTAGGAAAATATTAG

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-138)

MutL C terminal dimerisation domain (MutL_C)

(457-599)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5K7I0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

68.598

100

0.687

Multiple sequence alignment