Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   EL140_RS05120 Genome accession   NZ_LR134336
Coordinates   1008833..1010182 (-) Length   449 a.a.
NCBI ID   WP_000568721.1    Uniprot ID   -
Organism   Streptococcus oralis ATCC 35037 strain NCTC 11427     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1003833..1015182
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL140_RS05110 (NCTC11427_01007) - 1006043..1007914 (-) 1872 WP_000150976.1 Eco57I restriction-modification methylase domain-containing protein -
  EL140_RS05115 (NCTC11427_01008) vicX 1008022..1008831 (-) 810 WP_001290610.1 MBL fold metallo-hydrolase Regulator
  EL140_RS05120 (NCTC11427_01009) micB 1008833..1010182 (-) 1350 WP_000568721.1 cell wall metabolism sensor histidine kinase VicK Regulator
  EL140_RS05125 (NCTC11427_01010) yycF 1010175..1010882 (-) 708 WP_000722058.1 response regulator YycF -
  EL140_RS05130 (NCTC11427_01011) mutY 1010939..1012117 (-) 1179 WP_000886126.1 A/G-specific adenine glycosylase -
  EL140_RS05135 (NCTC11427_01012) pta 1012200..1013174 (-) 975 WP_000451577.1 phosphate acetyltransferase -
  EL140_RS05140 (NCTC11427_01013) - 1013218..1014114 (-) 897 WP_001210025.1 RluA family pseudouridine synthase -
  EL140_RS05145 (NCTC11427_01014) - 1014111..1014929 (-) 819 WP_000799063.1 NAD kinase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51607.95 Da        Isoelectric Point: 4.5770

>NTDB_id=1002007 EL140_RS05120 WP_000568721.1 1008833..1010182(-) (micB) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
MIEDIRQTILTSDFIFILILLGFILVVTLLLLENRRDNIRLKEINQKVKDLIAGDYSQVLDLQGSTEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILSYMTDGVLATNRRGQITMINDMAKKQLGVQKEDVLNKSILELLKIEDEYELRDLITQIPE
LTIDSQDVNGEYLSLRVRFALVRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALY
DPVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNTTSQLDVELINFTAFITFILNRFDKMRSQDDEKKYELVRDYPINSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDDQMILSIKDQGLGIPKQDLPKIFDRFYRVDRARSRAQGGTGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKDAVKEEIWEDEIED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1002007 EL140_RS05120 WP_000568721.1 1008833..1010182(-) (micB) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
ATGATTGAAGATATTAGACAAACTATTCTGACCAGTGATTTTATCTTTATCTTGATTTTACTTGGCTTTATCCTGGTGGT
GACCTTGCTGTTACTGGAAAATCGTCGGGATAATATCCGTCTAAAGGAGATAAATCAAAAGGTTAAGGACTTGATTGCAG
GTGATTATTCTCAAGTTTTGGACTTGCAAGGAAGTACAGAAATCACCAATATCACCAATAATCTGAACGATTTGTCAGAA
GTTATTCGTTTGACCCAAGAAAATCTGGAACAAGAGAGTAAACGATTGAACAGTATTCTTTCTTACATGACAGATGGCGT
TCTTGCGACCAATCGCCGTGGCCAGATTACTATGATCAACGATATGGCCAAGAAACAGCTCGGTGTGCAGAAAGAAGATG
TTCTGAATAAAAGCATCCTCGAATTGCTTAAGATAGAAGATGAGTATGAGTTGCGTGACCTGATTACACAGATTCCTGAG
TTGACGATTGACTCCCAGGATGTGAATGGTGAATATCTAAGCCTTCGTGTACGTTTTGCTCTGGTTCGCCGTGAGTCAGG
TTTTATCTCTGGTTTGGTTGCCGTTTTACATGATACGACCGAACAGGAGAAGGAAGAGCGTGAGCGAAGACTCTTTGTTT
CTAACGTGAGTCACGAGTTGCGAACTCCTTTGACCAGTGTTAAATCTTATCTTGAAGCCTTGGACGAGGGAGCCCTGTAT
GATCCTGTTGCTCCTGATTTTATCAAGGTTTCACTCGATGAAACCAACCGTATGATGCGGATGGTGACAGATCTCTTGCA
TCTCTCTCGTATTGATAATACGACAAGTCAGCTAGATGTGGAATTGATTAATTTTACAGCATTCATCACCTTTATTCTCA
ACCGCTTTGATAAGATGAGAAGTCAGGATGACGAGAAAAAATATGAGCTTGTCAGAGATTACCCTATTAATTCAGTTTGG
ATCGAGATTGATACCGATAAGATGACTCAGGTGATTGATAATATTCTTAACAATGCCATTAAGTACTCACCAGATGGTGG
GAAAATCACTGTCAGCATGAAAACTACTGATGACCAGATGATTTTATCCATCAAAGACCAAGGTCTAGGTATTCCAAAGC
AAGATTTGCCTAAGATTTTTGACCGCTTCTACCGTGTGGATCGTGCAAGAAGCCGGGCTCAAGGTGGAACTGGTCTAGGT
CTGGCGATCGCAAAAGAAATCATCAAACAACACAATGGCTTTATATGGGCCAAAAGTGAATACGGTAAGGGCTCAACCTT
TACCATAGTGCTCCCTTATGATAAGGATGCCGTAAAAGAAGAAATATGGGAGGACGAAATAGAAGACTAG

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(95-198)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

89.294

97.773

0.873
  vicK Streptococcus mutans UA159

70.896

89.532

0.635