Detailed information
Bioinformatically predicted
Overview
| Name | clpX | Type | Regulator |
| Locus tag | ABC807_RS03470 | Genome accession | NZ_CP156625 |
| Coordinates | 645464..646696 (+) | Length | 410 a.a. |
| NCBI ID | WP_024478652.1 | Uniprot ID | - |
| Organism | Streptococcus pneumoniae strain TL7/1993 | ||
| Function | require for competence development (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 636405..699428 | 645464..646696 | within | 0 |
Gene organization within MGE regions
Location: 636405..699428
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ABC807_RS03415 (ABC807_03415) | ugpC | 636405..637535 (+) | 1131 | WP_000229961.1 | sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC | - |
| ABC807_RS03420 (ABC807_03420) | - | 637682..637828 (-) | 147 | WP_000403100.1 | hypothetical protein | - |
| ABC807_RS03425 (ABC807_03425) | - | 638036..638794 (+) | 759 | WP_001287230.1 | class I SAM-dependent methyltransferase | - |
| ABC807_RS03430 (ABC807_03430) | - | 638881..639393 (+) | 513 | WP_001049323.1 | adenine phosphoribosyltransferase | - |
| ABC807_RS03435 (ABC807_03435) | metA | 639575..640519 (+) | 945 | WP_001122712.1 | homoserine O-succinyltransferase | - |
| ABC807_RS03440 (ABC807_03440) | - | 640528..641205 (+) | 678 | WP_000221614.1 | DnaD domain-containing protein | - |
| ABC807_RS03445 (ABC807_03445) | tpiA | 641303..642061 (+) | 759 | WP_000087897.1 | triose-phosphate isomerase | - |
| ABC807_RS03450 (ABC807_03450) | lytC | 642099..643604 (+) | 1506 | WP_078139284.1 | choline binding-anchored murein hydrolase LytC | - |
| ABC807_RS03455 (ABC807_03455) | - | 644103..644621 (+) | 519 | WP_000229860.1 | Dps family protein | - |
| ABC807_RS03460 (ABC807_03460) | - | 644751..645257 (+) | 507 | WP_000162467.1 | dihydrofolate reductase | - |
| ABC807_RS03465 (ABC807_03465) | - | 645257..645427 (+) | 171 | WP_000442260.1 | hypothetical protein | - |
| ABC807_RS03470 (ABC807_03470) | clpX | 645464..646696 (+) | 1233 | WP_024478652.1 | ATP-dependent Clp protease ATP-binding subunit ClpX | Regulator |
| ABC807_RS03475 (ABC807_03475) | yihA | 646705..647292 (+) | 588 | WP_000422599.1 | ribosome biogenesis GTP-binding protein YihA/YsxC | - |
| ABC807_RS03480 (ABC807_03480) | - | 647303..647683 (+) | 381 | WP_001140412.1 | RidA family protein | - |
| ABC807_RS03485 (ABC807_03485) | rapZ | 647735..648625 (+) | 891 | WP_000163035.1 | RNase adapter RapZ | - |
| ABC807_RS03490 (ABC807_03490) | - | 648622..649599 (+) | 978 | WP_001231086.1 | YvcK family protein | - |
| ABC807_RS03495 (ABC807_03495) | whiA | 649596..650507 (+) | 912 | WP_000011306.1 | DNA-binding protein WhiA | - |
| ABC807_RS03500 (ABC807_03500) | - | 650595..651722 (-) | 1128 | WP_000266847.1 | site-specific integrase | - |
| ABC807_RS03505 (ABC807_03505) | - | 651864..652244 (-) | 381 | WP_000151192.1 | ImmA/IrrE family metallo-endopeptidase | - |
| ABC807_RS03510 (ABC807_03510) | - | 652467..653561 (-) | 1095 | WP_000156313.1 | hypothetical protein | - |
| ABC807_RS03515 (ABC807_03515) | - | 653563..653916 (-) | 354 | WP_000493111.1 | helix-turn-helix transcriptional regulator | - |
| ABC807_RS03520 (ABC807_03520) | - | 654314..654406 (-) | 93 | WP_000970295.1 | type I toxin-antitoxin system Fst family toxin | - |
| ABC807_RS03525 (ABC807_03525) | - | 654629..654718 (-) | 90 | WP_001810072.1 | hypothetical protein | - |
| ABC807_RS03530 (ABC807_03530) | - | 654942..655181 (-) | 240 | WP_000142893.1 | hypothetical protein | - |
| ABC807_RS03535 (ABC807_03535) | - | 655246..655437 (+) | 192 | WP_001112859.1 | DNA-binding protein | - |
| ABC807_RS03540 (ABC807_03540) | - | 655620..655811 (-) | 192 | WP_000834564.1 | hypothetical protein | - |
| ABC807_RS03545 (ABC807_03545) | - | 656152..656424 (+) | 273 | WP_000454230.1 | hypothetical protein | - |
| ABC807_RS03550 (ABC807_03550) | - | 656421..656615 (+) | 195 | WP_001050924.1 | hypothetical protein | - |
| ABC807_RS03555 (ABC807_03555) | - | 656615..656803 (+) | 189 | WP_001853687.1 | hypothetical protein | - |
| ABC807_RS03560 (ABC807_03560) | - | 656815..657156 (+) | 342 | WP_000189400.1 | hypothetical protein | - |
| ABC807_RS03565 (ABC807_03565) | - | 657157..657387 (+) | 231 | WP_000252078.1 | hypothetical protein | - |
| ABC807_RS03570 (ABC807_03570) | - | 657401..658123 (+) | 723 | WP_000544342.1 | HNH endonuclease signature motif containing protein | - |
| ABC807_RS03575 (ABC807_03575) | - | 658116..658598 (+) | 483 | WP_000157805.1 | siphovirus Gp157 family protein | - |
| ABC807_RS03580 (ABC807_03580) | - | 658607..658957 (+) | 351 | WP_223842484.1 | hypothetical protein | - |
| ABC807_RS03585 (ABC807_03585) | - | 658957..659442 (+) | 486 | WP_000696057.1 | hypothetical protein | - |
| ABC807_RS03590 (ABC807_03590) | - | 659405..660598 (+) | 1194 | WP_000028860.1 | DEAD/DEAH box helicase family protein | - |
| ABC807_RS03595 (ABC807_03595) | - | 660617..660934 (+) | 318 | WP_001044592.1 | hypothetical protein | - |
| ABC807_RS03600 (ABC807_03600) | - | 660934..661710 (+) | 777 | WP_000885998.1 | AAA family ATPase | - |
| ABC807_RS03605 (ABC807_03605) | - | 661730..662233 (+) | 504 | WP_000054337.1 | hypothetical protein | - |
| ABC807_RS03610 (ABC807_03610) | - | 662406..663227 (+) | 822 | WP_000097191.1 | bifunctional DNA primase/polymerase | - |
| ABC807_RS03615 (ABC807_03615) | - | 663230..664573 (+) | 1344 | WP_000580029.1 | virulence-associated E family protein | - |
| ABC807_RS03620 (ABC807_03620) | - | 664866..665018 (+) | 153 | WP_000122743.1 | hypothetical protein | - |
| ABC807_RS03625 (ABC807_03625) | - | 665018..665356 (+) | 339 | WP_000119453.1 | hypothetical protein | - |
| ABC807_RS03630 (ABC807_03630) | - | 665507..665821 (+) | 315 | WP_000391853.1 | hypothetical protein | - |
| ABC807_RS03635 (ABC807_03635) | - | 665823..666350 (+) | 528 | WP_001041163.1 | DUF1642 domain-containing protein | - |
| ABC807_RS03640 (ABC807_03640) | - | 666412..666729 (+) | 318 | WP_001268499.1 | hypothetical protein | - |
| ABC807_RS03645 (ABC807_03645) | - | 666847..667269 (+) | 423 | WP_001030244.1 | DUF1492 domain-containing protein | - |
| ABC807_RS03655 (ABC807_03655) | - | 668539..669051 (+) | 513 | WP_000863690.1 | terminase small subunit | - |
| ABC807_RS03660 (ABC807_03660) | - | 669029..670327 (+) | 1299 | WP_000084412.1 | PBSX family phage terminase large subunit | - |
| ABC807_RS03665 (ABC807_03665) | - | 670339..671808 (+) | 1470 | WP_000285392.1 | phage portal protein | - |
| ABC807_RS03670 (ABC807_03670) | - | 671717..673354 (+) | 1638 | WP_164993540.1 | minor capsid protein | - |
| ABC807_RS03675 (ABC807_03675) | - | 673356..673565 (+) | 210 | WP_000651746.1 | hypothetical protein | - |
| ABC807_RS03680 (ABC807_03680) | - | 673562..673975 (+) | 414 | WP_000565273.1 | HD domain-containing protein | - |
| ABC807_RS03685 (ABC807_03685) | - | 674017..674190 (+) | 174 | WP_000356388.1 | hypothetical protein | - |
| ABC807_RS03690 (ABC807_03690) | - | 674457..674981 (+) | 525 | WP_001288018.1 | DUF4355 domain-containing protein | - |
| ABC807_RS03695 (ABC807_03695) | - | 675004..676029 (+) | 1026 | WP_000863393.1 | carbohydrate-binding protein | - |
| ABC807_RS03700 (ABC807_03700) | - | 676039..676227 (+) | 189 | WP_000669348.1 | hypothetical protein | - |
| ABC807_RS03705 (ABC807_03705) | - | 676229..676540 (+) | 312 | WP_000021218.1 | phage head-tail connector protein | - |
| ABC807_RS03710 (ABC807_03710) | - | 676521..676859 (+) | 339 | WP_000478943.1 | hypothetical protein | - |
| ABC807_RS03715 (ABC807_03715) | - | 676834..677349 (+) | 516 | WP_000015940.1 | HK97-gp10 family putative phage morphogenesis protein | - |
| ABC807_RS03720 (ABC807_03720) | - | 677346..677714 (+) | 369 | WP_000608235.1 | hypothetical protein | - |
| ABC807_RS03725 (ABC807_03725) | - | 677717..678130 (+) | 414 | WP_000880665.1 | phage tail tube protein | - |
| ABC807_RS03730 (ABC807_03730) | - | 678135..678515 (+) | 381 | WP_001185631.1 | DUF6096 family protein | - |
| ABC807_RS03735 (ABC807_03735) | - | 678554..678904 (+) | 351 | WP_000478007.1 | hypothetical protein | - |
| ABC807_RS03740 (ABC807_03740) | - | 678891..682484 (+) | 3594 | WP_000212166.1 | hypothetical protein | - |
| ABC807_RS03745 (ABC807_03745) | - | 682493..682843 (+) | 351 | WP_000068023.1 | DUF6711 family protein | - |
| ABC807_RS03750 (ABC807_03750) | - | 682848..689291 (+) | 6444 | WP_000339678.1 | tail fiber domain-containing protein | - |
| ABC807_RS03755 (ABC807_03755) | - | 689288..689404 (+) | 117 | Protein_691 | dihydrodipicolinate reductase | - |
| ABC807_RS03760 (ABC807_03760) | - | 689385..689588 (+) | 204 | WP_001091119.1 | hypothetical protein | - |
| ABC807_RS03765 (ABC807_03765) | - | 689591..689941 (+) | 351 | WP_000852249.1 | hypothetical protein | - |
| ABC807_RS03770 (ABC807_03770) | - | 689951..690250 (+) | 300 | WP_001810279.1 | hypothetical protein | - |
| ABC807_RS03775 (ABC807_03775) | - | 690254..690589 (+) | 336 | WP_001186239.1 | phage holin | - |
| ABC807_RS03780 (ABC807_03780) | - | 690589..691545 (+) | 957 | WP_000350525.1 | N-acetylmuramoyl-L-alanine amidase family protein | - |
| ABC807_RS03785 (ABC807_03785) | - | 691798..692766 (-) | 969 | WP_000081003.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| ABC807_RS03790 (ABC807_03790) | cdaA | 692902..693759 (+) | 858 | WP_001011058.1 | diadenylate cyclase CdaA | - |
| ABC807_RS03795 (ABC807_03795) | - | 693746..694525 (+) | 780 | WP_000742290.1 | CdaR family protein | - |
| ABC807_RS03800 (ABC807_03800) | glmM | 694549..695901 (+) | 1353 | WP_000521418.1 | phosphoglucosamine mutase | - |
| ABC807_RS03805 (ABC807_03805) | - | 695975..696349 (+) | 375 | WP_001050086.1 | DUF1149 family protein | - |
| ABC807_RS03810 (ABC807_03810) | - | 696351..697199 (+) | 849 | WP_000762061.1 | DegV family protein | - |
| ABC807_RS03815 (ABC807_03815) | dapB | 697465..698232 (+) | 768 | WP_000027897.1 | 4-hydroxy-tetrahydrodipicolinate reductase | - |
| ABC807_RS03820 (ABC807_03820) | - | 698229..699428 (+) | 1200 | WP_001858603.1 | CCA tRNA nucleotidyltransferase | - |
Sequence
Protein
Download Length: 410 a.a. Molecular weight: 45726.24 Da Isoelectric Point: 4.4240
>NTDB_id=1001837 ABC807_RS03470 WP_024478652.1 645464..646696(+) (clpX) [Streptococcus pneumoniae strain TL7/1993]
MPTTRNNDMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA
MPTTRNNDMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA
Nucleotide
Download Length: 1233 bp
>NTDB_id=1001837 ABC807_RS03470 WP_024478652.1 645464..646696(+) (clpX) [Streptococcus pneumoniae strain TL7/1993]
ATGCCTACAACTAGGAATAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAGCCAAGAAGAAGTACAAAAAATAAT
CGCTGGGAACAACGCCTTTATCTGTAATGAATGTGTAGAGTTAGCCCAGGAAATCATTCGGGAAGAGTTGGCGGAAGAAG
TCTTGGCAGACTTGTCTGAGGTACCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATCGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCAGTTTACAATCACTACAAACGCATCAATTTCCACGATACGCGTGAAGAGTCGGAAGA
TGTAGATTTGCAGAAGTCAAACATCTTGATGATTGGCCCAACCGGTTCAGGGAAAACTTTCCTTGCTCAGACCTTGGCTA
AGAGCTTAAATGTGCCTTTTGCGATTGCGGATGCGACAGCTCTTACCGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATACTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTACCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTAATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG
ATGCCTACAACTAGGAATAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAGCCAAGAAGAAGTACAAAAAATAAT
CGCTGGGAACAACGCCTTTATCTGTAATGAATGTGTAGAGTTAGCCCAGGAAATCATTCGGGAAGAGTTGGCGGAAGAAG
TCTTGGCAGACTTGTCTGAGGTACCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATCGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCAGTTTACAATCACTACAAACGCATCAATTTCCACGATACGCGTGAAGAGTCGGAAGA
TGTAGATTTGCAGAAGTCAAACATCTTGATGATTGGCCCAACCGGTTCAGGGAAAACTTTCCTTGCTCAGACCTTGGCTA
AGAGCTTAAATGTGCCTTTTGCGATTGCGGATGCGACAGCTCTTACCGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATACTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTACCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTAATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpX | Streptococcus mutans UA159 |
86.341 |
100 |
0.863 |
| clpX | Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 |
57.214 |
98.049 |
0.561 |