Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   EL133_RS02320 Genome accession   NZ_LR134323
Coordinates   458962..459603 (+) Length   213 a.a.
NCBI ID   WP_006739571.1    Uniprot ID   G5KCR6
Organism   Streptococcus urinalis strain NCTC13766     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 453962..464603
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL133_RS02300 (NCTC13766_00462) - 454545..455282 (+) 738 WP_006739689.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  EL133_RS02305 (NCTC13766_00463) pknB 455282..457183 (+) 1902 WP_006739098.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  EL133_RS02310 (NCTC13766_00464) liaF 457273..457968 (+) 696 WP_006738642.1 cell wall-active antibiotics response protein LiaF -
  EL133_RS02315 (NCTC13766_00465) - 457965..458990 (+) 1026 WP_006740072.1 sensor histidine kinase -
  EL133_RS02320 (NCTC13766_00466) vraR 458962..459603 (+) 642 WP_006739571.1 response regulator transcription factor Regulator
  EL133_RS02325 (NCTC13766_00467) - 459640..461040 (+) 1401 WP_006739756.1 Cof-type HAD-IIB family hydrolase -
  EL133_RS02330 (NCTC13766_00468) - 461040..461402 (+) 363 WP_006739454.1 S1 RNA-binding domain-containing protein -
  EL133_RS02335 (NCTC13766_00469) cysK 461426..462343 (-) 918 WP_006738535.1 cysteine synthase A -
  EL133_RS02340 (NCTC13766_00470) - 462435..463085 (-) 651 WP_006740367.1 YigZ family protein -
  EL133_RS02345 (NCTC13766_00471) comFA/cflA 463142..464443 (+) 1302 WP_006738633.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 24002.60 Da        Isoelectric Point: 4.6302

>NTDB_id=1001653 EL133_RS02320 WP_006739571.1 458962..459603(+) (vraR) [Streptococcus urinalis strain NCTC13766]
MTTIKVVLIDDHEMVRMGLKSFLNMQSDIEVIAEGVNGNDGIKLGLELKPDVIVMDLVMPEVDGVEATLSILKEWSEAKI
LVLTSYLDNEKIYPVIEAGVKGYMLKTSSAAEILNAIRKVANRQEAIETEVDKKIKNHQDNPELHEELTAREYDILYLLA
KGFDNQTIADELYISLKTVKTHVSNILAKLQVDDRTQAVVYAFRHHLVPQDDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=1001653 EL133_RS02320 WP_006739571.1 458962..459603(+) (vraR) [Streptococcus urinalis strain NCTC13766]
ATGACAACAATAAAAGTAGTATTGATTGACGATCATGAGATGGTTAGAATGGGACTAAAAAGCTTTCTTAATATGCAATC
AGATATAGAAGTCATTGCTGAAGGTGTGAACGGTAATGATGGCATCAAACTAGGGTTAGAGTTGAAACCAGATGTTATCG
TTATGGATTTAGTTATGCCAGAAGTAGATGGTGTGGAGGCAACCTTAAGTATTCTAAAAGAATGGTCAGAAGCAAAAATC
TTAGTTCTTACATCTTACTTAGATAATGAAAAAATTTACCCTGTCATTGAAGCGGGAGTCAAAGGTTACATGTTAAAAAC
ATCTAGTGCTGCAGAAATCTTAAATGCTATTAGAAAAGTAGCCAATAGACAAGAAGCTATTGAGACAGAAGTTGATAAAA
AAATCAAGAACCATCAAGATAATCCAGAATTACATGAAGAATTAACAGCCAGAGAATATGATATATTATATTTATTAGCT
AAAGGATTTGATAATCAAACCATTGCTGATGAGTTATATATTTCCTTAAAAACGGTTAAAACACATGTTTCAAATATTTT
AGCAAAATTACAAGTTGATGACCGAACTCAAGCAGTTGTTTATGCCTTTAGACATCATTTAGTCCCACAAGATGACAATT
AA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5KCR6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.657

97.183

0.512
  degU Bacillus subtilis subsp. subtilis str. 168

36.283

100

0.385

Multiple sequence alignment