Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   EL139_RS03835 Genome accession   NZ_LR134316
Coordinates   716416..718398 (+) Length   660 a.a.
NCBI ID   WP_111717762.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 711416..723398
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL139_RS03820 (NCTC6181_00778) argR 712958..713395 (+) 438 WP_003055516.1 arginine repressor -
  EL139_RS03825 (NCTC6181_00779) - 713392..713745 (+) 354 WP_111717764.1 YlbF family regulator -
  EL139_RS03830 (NCTC6181_00780) hexA 713732..716287 (+) 2556 WP_111717763.1 DNA mismatch repair protein MutS Machinery gene
  EL139_RS03835 (NCTC6181_00781) hexB 716416..718398 (+) 1983 WP_111717762.1 DNA mismatch repair endonuclease MutL Machinery gene
  EL139_RS03840 (NCTC6181_00782) - 718409..719629 (+) 1221 WP_111717761.1 MFS transporter -
  EL139_RS03845 (NCTC6181_00783) ruvA 719631..720224 (+) 594 WP_111717760.1 Holliday junction branch migration protein RuvA Machinery gene
  EL139_RS03850 (NCTC6181_00784) - 720234..720806 (+) 573 WP_111717759.1 DNA-3-methyladenine glycosylase I -
  EL139_RS03855 (NCTC6181_00785) - 720809..721096 (+) 288 Protein_715 VOC family protein -
  EL139_RS03860 (NCTC6181_00786) cinA 721286..722557 (+) 1272 WP_111717758.1 competence/damage-inducible protein A Machinery gene

Sequence

Protein


Download         Length: 660 a.a.        Molecular weight: 74537.89 Da        Isoelectric Point: 5.3685

>NTDB_id=1001344 EL139_RS03835 WP_111717762.1 716416..718398(+) (hexB) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181]
MTNIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQVTIDIEESGLKKIQITDNGEGMSPEDLPLSLRRHATSK
IKSQSDLFRIRTLGFRGEALPSVASISKITIKTATKEDNHGSLLVAIGGEIETLEETSTPVGTKIKVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVSFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTAKKMIAISKADLDFEVSGYVSLP
ELTRANRNYMTILINGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALIST
AISESLKEQDLIPDALENLAKSSTRHFSKPEQTQLPLQSKGLYYDPQRNDFFVKESDVSEKIPESNFHDIEIDKTVKDQR
TEQFPDLGQYTGASSVKHASRSQDEITDDDHPGLDLKNKQKLSQMLTRLENEEQSVFPELDYFGQMHGTYLFAQGKDGLF
IIDQHAAQERVKYEYYRDKIGEVDSSLQQLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEE
EIASGVYEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYNCPHGRPVLINFSKADM
EKMFRRIQENHTSLRELGKY

Nucleotide


Download         Length: 1983 bp        

>NTDB_id=1001344 EL139_RS03835 WP_111717762.1 716416..718398(+) (hexB) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181]
ATGACAAACATTATTGAATTACCAGAAGTTCTCGCCAACCAAATTGCAGCTGGTGAAGTTGTAGAAAGGCCAGCGAGTGT
TGTCAAGGAATTGGTTGAGAATGCTATCGATGCTAAGAGTAGCCAAGTTACCATTGATATTGAAGAGTCTGGTCTCAAAA
AGATACAGATTACGGACAATGGTGAAGGGATGTCGCCTGAAGACCTTCCTTTGAGTTTGCGGCGACATGCTACCAGTAAA
ATAAAAAGTCAAAGTGATCTCTTTCGAATTAGAACGCTTGGTTTTAGGGGAGAAGCTTTACCATCGGTTGCTTCTATCAG
TAAAATCACAATAAAAACAGCTACTAAGGAAGATAATCACGGTTCTCTTTTAGTTGCTATCGGCGGAGAAATTGAAACGC
TCGAGGAAACGTCGACGCCTGTAGGTACCAAGATTAAGGTGGAAAACCTTTTTTATAACACGCCTGCTCGCCTCAAATAC
ATGAAAAGTTTACAGGCAGAGTTAGCCCATATTGTTGATGTGGTCAATCGTTTGAGTTTGGCACATCCAGAAGTTTCTTT
CACCCTTATTAGTGATGGGCGTCAATTAACTCAGACATCAGGGACGGGGGACCTGCGGCAGGCTATTGCAGGGATTTATG
GCTTGAATACTGCCAAAAAAATGATTGCTATTTCCAAAGCCGATTTGGACTTTGAAGTGTCGGGCTATGTCAGTTTACCA
GAGTTGACACGTGCCAACCGCAATTATATGACCATTTTAATCAATGGACGCTACATTAAAAATTTCTTGCTCAACCGGGC
TATTTTAGACGGTTACGGCTCTAAGTTGATGGTTGGACGTTTCCCAATAGTGGTGATTGATATTCAGATTGACCCCTATT
TGGCCGATGTCAATGTTCACCCTACTAAGCAAGAGGTCCGTATTTCAAAAGAGCGTGAGTTGATGGCTTTAATTAGTACG
GCGATTTCTGAAAGTCTTAAGGAGCAAGATTTGATTCCAGATGCTCTGGAGAACTTAGCTAAATCAAGCACACGACACTT
TTCTAAACCAGAGCAAACACAACTTCCATTACAATCTAAAGGGCTTTATTATGATCCTCAAAGAAATGACTTTTTTGTTA
AAGAATCGGATGTTTCTGAAAAAATACCTGAGAGTAATTTTCATGATATAGAGATTGACAAGACTGTAAAGGATCAAAGG
ACGGAACAGTTTCCTGATTTAGGACAGTATACAGGGGCTTCCTCAGTAAAACATGCTAGTCGATCACAGGATGAGATAAC
TGATGATGATCACCCTGGACTTGATTTGAAAAACAAACAGAAATTATCTCAAATGCTAACCCGTTTGGAAAATGAAGAGC
AATCAGTATTTCCCGAATTGGATTATTTTGGTCAGATGCACGGCACTTATCTCTTTGCTCAGGGAAAAGATGGTTTATTT
ATCATTGACCAACACGCTGCCCAAGAGCGAGTTAAATACGAATATTATCGTGATAAGATAGGTGAGGTTGACAGTAGTTT
ACAGCAATTGTTGGTGCCCTATTTGTTTGAGTTTTCCGGCTCGGATTTCATTAACTTACAGGAGAAAATGGCACTCTTAA
ATGAAGTTGGTATCTTCTTAGAAGTTTATGGGCACAATACTTTCATTTTGAGGGAGCATCCTATCTGGATGAAAGAAGAA
GAGATTGCATCTGGTGTCTATGAAATGTGTGACATGTTACTTCTAACCAATGAGGTATCTATTAAAACTTACCGAGCAGA
GTTAGCTATTATGATGAGTTGTAAACGATCTATCAAGGCAAATCATAGCTTGGATGATTATTCAGCAAGAAATCTGCTAC
TACAATTAGCCCAATGTCAAAATCCTTATAACTGCCCTCATGGTAGACCCGTGTTGATTAATTTCAGTAAGGCAGATATG
GAAAAAATGTTCCGTCGTATCCAAGAAAATCATACTAGCCTGCGAGAGCTAGGAAAATATTAG

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(462-604)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-118)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

68.127

100

0.683

Multiple sequence alignment