Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2678261..2678586 Replicon chromosome
Accession NZ_CP020102
Organism Bacillus subtilis strain NCIB 3610

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag B4U62_RS14055 Protein ID WP_004398662.1
Coordinates 2678261..2678440 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2678364..2678586 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B4U62_RS14045 2677487..2677624 - 138 WP_003229934.1 hypothetical protein -
B4U62_RS14050 2677666..2678115 - 450 WP_003229933.1 phage portal protein -
B4U62_RS14055 2678261..2678440 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- 2678364..2678586 - 223 NuclAT_0 - Antitoxin
- 2678364..2678586 - 223 NuclAT_0 - Antitoxin
- 2678364..2678586 - 223 NuclAT_0 - Antitoxin
- 2678364..2678586 - 223 NuclAT_0 - Antitoxin
B4U62_RS22640 2678820..2678909 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
B4U62_RS14065 2679163..2679606 - 444 WP_003229930.1 phage tail tube protein -
B4U62_RS14070 2679609..2681009 - 1401 WP_003229929.1 phage tail sheath family protein -
B4U62_RS14075 2681010..2681201 - 192 WP_010886574.1 hypothetical protein -
B4U62_RS14080 2681198..2681635 - 438 WP_003229927.1 hypothetical protein -
B4U62_RS14085 2681648..2682151 - 504 WP_003246050.1 HK97 gp10 family phage protein -
B4U62_RS14090 2682148..2682510 - 363 WP_003229925.1 YqbH/XkdH family protein -
B4U62_RS14095 2682507..2682902 - 396 WP_004398566.1 DUF3199 family protein -
B4U62_RS14100 2682906..2683217 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2647774..2699264 51490


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T74094 WP_004398662.1 NZ_CP020102:2678261-2678440 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

>T74094 NZ_CP020102:2678261-2678440 [Bacillus subtilis]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG

Antitoxin


Download         Length: 223 bp

>AT74094 NZ_CP020102:c2678586-2678364 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References