Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2677612..2677937 Replicon chromosome
Accession NZ_CP016852
Organism Bacillus subtilis subsp. subtilis strain 168G

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag BFI33_RS14180 Protein ID WP_004398662.1
Coordinates 2677612..2677791 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2677715..2677937 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BFI33_RS14170 2676838..2676975 - 138 WP_003229934.1 hypothetical protein -
BFI33_RS14175 2677017..2677466 - 450 WP_003229933.1 phage portal protein -
BFI33_RS14180 2677612..2677791 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- 2677715..2677937 - 223 NuclAT_0 - Antitoxin
- 2677715..2677937 - 223 NuclAT_0 - Antitoxin
- 2677715..2677937 - 223 NuclAT_0 - Antitoxin
- 2677715..2677937 - 223 NuclAT_0 - Antitoxin
BFI33_RS22870 2678171..2678260 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
BFI33_RS14185 2678514..2678957 - 444 WP_003229930.1 phage tail tube protein -
BFI33_RS14190 2678960..2680360 - 1401 WP_003229929.1 phage tail sheath family protein -
BFI33_RS14195 2680361..2680552 - 192 WP_010886574.1 hypothetical protein -
BFI33_RS14200 2680549..2680986 - 438 WP_003229927.1 hypothetical protein -
BFI33_RS14205 2680999..2681502 - 504 WP_003246050.1 HK97 gp10 family phage protein -
BFI33_RS14210 2681499..2681861 - 363 WP_003229925.1 YqbH/XkdH family protein -
BFI33_RS14215 2681858..2682253 - 396 WP_004398566.1 DUF3199 family protein -
BFI33_RS14220 2682257..2682568 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2647125..2698615 51490


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T65218 WP_004398662.1 NZ_CP016852:2677612-2677791 [Bacillus subtilis subsp. subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

>T65218 NZ_CP016852:2677612-2677791 [Bacillus subtilis subsp. subtilis]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG

Antitoxin


Download         Length: 223 bp

>AT65218 NZ_CP016852:c2677937-2677715 [Bacillus subtilis subsp. subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References