Detailed information of TA system    

experimentalExperimentally validated    

Overview

TA module


Type III Classification (family/domain) cptIN/-
Location 296200..296785 Replicon draft genome
Accession NC_021010
Organism Eubacterium rectale DSM 17629

Toxin (Protein)


Gene name cptN Uniprot ID -
Locus tag EUR_02830 Protein ID YP_007771623.1
Coordinates 296297..296785 (+) Length 163 a.a.

Antitoxin (RNA)


Gene name cptI
Locus tag -
Coordinates 296200..296244 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EUR_RS01355 (EUR_02760) 291360..292304 + 945 WP_015515669.1 hypothetical protein -
EUR_RS01360 (EUR_02770) 292301..293077 + 777 WP_015515670.1 protein-ADP-ribose hydrolase -
EUR_RS01365 (EUR_02780) 293295..293936 + 642 WP_015515671.1 helix-turn-helix transcriptional regulator -
EUR_RS01370 (EUR_02790) 293996..294409 + 414 WP_015515672.1 hypothetical protein -
EUR_RS01375 (EUR_02800) 294434..294619 + 186 WP_015515673.1 hypothetical protein -
EUR_RS01380 (EUR_02810) 294693..295028 - 336 WP_012741562.1 helix-turn-helix transcriptional regulator -
EUR_RS01385 (EUR_02820) 295195..296124 + 930 WP_015515674.1 RNA ligase family protein -
- 296200..296244 + 45 - - Antitoxin
EUR_RS01390 (EUR_02830) 296297..296785 + 489 WP_015515675.1 hypothetical protein Toxin
EUR_RS01395 (EUR_02840) 296942..297763 + 822 WP_015515676.1 M15 family metallopeptidase -
EUR_RS01400 (EUR_02850) 297776..298696 - 921 WP_015515677.1 aldo/keto reductase -
EUR_RS01405 (EUR_02860) 298717..299895 - 1179 WP_015515678.1 flagellin lysine-N-methylase -
EUR_RS01410 (EUR_02870) 299951..301339 - 1389 WP_015515679.1 MATE family efflux transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 19177.10 Da        Isoelectric Point: 9.8225

>T6374 YP_007771623.1 NC_021010:296297-296785 [Agathobacter rectalis DSM 17629]
MIRNGFYIIKDRFFSDMSDPYLKGNKKQNRPHYYCFEDSNYNGIYWMIPLSSRIDKYKKIVSKRTGKGRNCDIIHIVKLD
DSHESAFLIQDMFPISDKYIEREYTIAGNHLRLTSEHAAKEIEQKARKVLGMLKRGIKFTPTQPDIQKIYERLQQDLPAT
HL

Download         Length: 489 bp

>T6374 NC_021010:296297-296785 [Agathobacter rectalis DSM 17629]
ATGATAAGGAATGGTTTTTATATTATCAAAGATAGATTTTTTTCGGATATGTCGGATCCATATTTGAAAGGAAATAAAAA
ACAAAATAGACCACACTACTATTGTTTTGAAGATAGCAATTATAATGGAATATATTGGATGATTCCTCTTTCAAGTCGGA
TTGATAAGTATAAGAAAATAGTAAGTAAAAGAACCGGTAAAGGAAGAAACTGTGATATAATTCACATTGTGAAACTTGAT
GATAGTCATGAAAGCGCTTTTTTGATACAGGATATGTTTCCAATTTCAGACAAATATATAGAACGGGAATACACTATAGC
AGGTAATCATCTTCGTCTAACCAGTGAACATGCTGCAAAAGAAATTGAACAAAAAGCAAGAAAAGTTTTGGGAATGCTGA
AAAGAGGAATAAAATTTACTCCAACCCAACCAGATATACAGAAAATATATGAGAGGCTGCAACAGGATTTACCAGCAACA
CATTTGTAA

Antitoxin


Download         Length: 45 bp

>AT6374 NC_021010:296200-296244 [Agathobacter rectalis DSM 17629]
TGAAAGTTTACCACTGACCGATATGTGGTATATAAATGGTCGGGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
T6372 Coprococcus catus GD/7

39.355

96.875

0.381
T6373 Ruminococcus torques L2-14

34.839

95.679

0.333

Multiple sequence alignment    


Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References

(1) Tim R Blower et al. (2012) Identification and classification of bacterial Type III toxin-antitoxin systems encoded in chromosomal and plasmid genomes. Nucleic Acids Research 40(13):6158-73. [PubMed:22434880] experimental


experimental experimental literature