Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 1933573..1933898 Replicon chromosome
Accession NZ_CP015375
Organism Bacillus subtilis subsp. subtilis strain KCTC 3135

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag AS891_RS10050 Protein ID WP_004398662.1
Coordinates 1933719..1933898 (-) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 1933573..1933795 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AS891_RS10010 1928942..1929253 + 312 WP_003229923.1 YqbF domain-containing protein -
AS891_RS10015 1929257..1929652 + 396 WP_004398566.1 DUF3199 family protein -
AS891_RS10020 1929649..1930011 + 363 WP_003229925.1 YqbH/XkdH family protein -
AS891_RS10025 1930008..1930511 + 504 WP_003246050.1 HK97 gp10 family phage protein -
AS891_RS10030 1930524..1930961 + 438 WP_003229927.1 hypothetical protein -
AS891_RS10035 1930958..1931149 + 192 WP_010886574.1 hypothetical protein -
AS891_RS10040 1931150..1932550 + 1401 WP_003229929.1 phage tail sheath family protein -
AS891_RS10045 1932553..1932996 + 444 WP_003229930.1 phage tail tube protein -
AS891_RS22880 1933250..1933339 - 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
- 1933573..1933795 + 223 NuclAT_0 - Antitoxin
- 1933573..1933795 + 223 NuclAT_0 - Antitoxin
- 1933573..1933795 + 223 NuclAT_0 - Antitoxin
- 1933573..1933795 + 223 NuclAT_0 - Antitoxin
AS891_RS10050 1933719..1933898 - 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
AS891_RS10055 1934044..1934493 + 450 WP_003229933.1 phage portal protein -
AS891_RS10060 1934535..1934672 + 138 WP_003229934.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 1912895..1974595 61700


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T62914 WP_004398662.1 NZ_CP015375:c1933898-1933719 [Bacillus subtilis subsp. subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

>T62914 NZ_CP015375:c1933898-1933719 [Bacillus subtilis subsp. subtilis]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG

Antitoxin


Download         Length: 223 bp

>AT62914 NZ_CP015375:1933573-1933795 [Bacillus subtilis subsp. subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References