Detailed information of TA system TA062914

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 1933573..1933898
• Replicon: chromosome
• Accession: NZ_CP015375
• Organism: Bacillus subtilis subsp. subtilis strain KCTC 3135

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: P54373
• Locus tag: AS891_RS10050
• Protein ID: WP_004398662.1
• Coordinates: 1933719..1933898 (-)
• Length: 60 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	1933573..1933795 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AS891_RS10010	1928942..1929253	+	312	WP_003229923.1	YqbF domain-containing protein	-
AS891_RS10015	1929257..1929652	+	396	WP_004398566.1	DUF3199 family protein	-
AS891_RS10020	1929649..1930011	+	363	WP_003229925.1	YqbH/XkdH family protein	-
AS891_RS10025	1930008..1930511	+	504	WP_003246050.1	HK97 gp10 family phage protein	-
AS891_RS10030	1930524..1930961	+	438	WP_003229927.1	hypothetical protein	-
AS891_RS10035	1930958..1931149	+	192	WP_010886574.1	hypothetical protein	-
AS891_RS10040	1931150..1932550	+	1401	WP_003229929.1	phage tail sheath family protein	-
AS891_RS10045	1932553..1932996	+	444	WP_003229930.1	phage tail tube protein	-
AS891_RS22880	1933250..1933339	-	90	WP_075058862.1	type I toxin-antitoxin system toxin BsrH	-
-	1933573..1933795	+	223	NuclAT_0	-	Antitoxin
-	1933573..1933795	+	223	NuclAT_0	-	Antitoxin
-	1933573..1933795	+	223	NuclAT_0	-	Antitoxin
-	1933573..1933795	+	223	NuclAT_0	-	Antitoxin
AS891_RS10050	1933719..1933898	-	180	WP_004398662.1	type I toxin-antitoxin system toxin TxpA	Toxin
AS891_RS10055	1934044..1934493	+	450	WP_003229933.1	phage portal protein	-
AS891_RS10060	1934535..1934672	+	138	WP_003229934.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	Similar MGE(s) Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE. Detail Genome accession Organism MGE type Related TA Coordinates Mash distance View NC_000964 Bacillus subtilis subsp. subtilis str. 168 Prophage TA006322, TA010201, TA020260 2645490..2699243 0.003	inside	Prophage	-	-	1912895..1974595	61700

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 60 a.a.
• Molecular weight: 6739.19 Da
• Isoelectric Point: 8.0370

>T62914 WP_004398662.1 NZ_CP015375:c1933898-1933719 [Bacillus subtilis subsp. subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Nucleotide

• Length: 180 bp

>T62914 NZ_CP015375:c1933898-1933719 [Bacillus subtilis subsp. subtilis]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG

Antitoxin

Nucleotide

• Length: 223 bp

>AT62914 NZ_CP015375:1933573-1933795 [Bacillus subtilis subsp. subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Structures

Toxin

• AlphaFold DB: A0A164X333

Antitoxin