Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2518925..2519250 Replicon chromosome
Accession NZ_CP014166
Organism Bacillus subtilis subsp. subtilis strain CU1050

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag AWM80_RS13055 Protein ID WP_004398662.1
Coordinates 2518925..2519104 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2519028..2519250 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AWM80_RS13045 2518151..2518288 - 138 WP_003229934.1 hypothetical protein -
AWM80_RS13050 2518330..2518779 - 450 WP_003229933.1 phage portal protein -
AWM80_RS13055 2518925..2519104 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- 2519028..2519250 - 223 NuclAT_0 - Antitoxin
- 2519028..2519250 - 223 NuclAT_0 - Antitoxin
- 2519028..2519250 - 223 NuclAT_0 - Antitoxin
- 2519028..2519250 - 223 NuclAT_0 - Antitoxin
AWM80_RS21685 2519484..2519573 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
AWM80_RS13060 2519827..2520270 - 444 WP_003229930.1 phage tail tube protein -
AWM80_RS13065 2520273..2521673 - 1401 WP_003229929.1 phage tail sheath family protein -
AWM80_RS13070 2521674..2521865 - 192 WP_010886574.1 hypothetical protein -
AWM80_RS13075 2521862..2522299 - 438 WP_003229927.1 hypothetical protein -
AWM80_RS13080 2522312..2522815 - 504 WP_003246050.1 HK97 gp10 family phage protein -
AWM80_RS13085 2522812..2523174 - 363 WP_003229925.1 YqbH/XkdH family protein -
AWM80_RS13090 2523171..2523566 - 396 WP_004398566.1 DUF3199 family protein -
AWM80_RS13095 2523570..2523881 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2488438..2543789 55351


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T60328 WP_004398662.1 NZ_CP014166:2518925-2519104 [Bacillus subtilis subsp. subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

>T60328 NZ_CP014166:2518925-2519104 [Bacillus subtilis subsp. subtilis]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG

Antitoxin


Download         Length: 223 bp

>AT60328 NZ_CP014166:c2519250-2519028 [Bacillus subtilis subsp. subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References