Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-ratA/- |
Location | 3453284..3453609 | Replicon | chromosome |
Accession | NZ_CP011882 | ||
Organism | Bacillus subtilis strain TO-A JPC |
Toxin (Protein)
Gene name | txpA | Uniprot ID | P54373 |
Locus tag | ABU16_RS17855 | Protein ID | WP_004398662.1 |
Coordinates | 3453284..3453463 (+) | Length | 60 a.a. |
Antitoxin (RNA)
Gene name | ratA | ||
Locus tag | - | ||
Coordinates | 3453387..3453609 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ABU16_RS22070 | 3452510..3452647 | - | 138 | WP_003229934.1 | hypothetical protein | - |
ABU16_RS17850 | 3452689..3453138 | - | 450 | WP_003229933.1 | phage portal protein | - |
ABU16_RS17855 | 3453284..3453463 | + | 180 | WP_004398662.1 | type I toxin-antitoxin system toxin TxpA | Toxin |
- | 3453387..3453609 | - | 223 | NuclAT_0 | - | Antitoxin |
- | 3453387..3453609 | - | 223 | NuclAT_0 | - | Antitoxin |
- | 3453387..3453609 | - | 223 | NuclAT_0 | - | Antitoxin |
- | 3453387..3453609 | - | 223 | NuclAT_0 | - | Antitoxin |
ABU16_RS22520 | 3453843..3453932 | + | 90 | WP_075058862.1 | type I toxin-antitoxin system toxin BsrH | - |
ABU16_RS17860 | 3454186..3454629 | - | 444 | WP_003229930.1 | phage tail tube protein | - |
ABU16_RS17865 | 3454632..3456032 | - | 1401 | WP_003229929.1 | phage tail sheath family protein | - |
ABU16_RS17870 | 3456033..3456224 | - | 192 | WP_010886574.1 | hypothetical protein | - |
ABU16_RS17875 | 3456221..3456658 | - | 438 | WP_003229927.1 | hypothetical protein | - |
ABU16_RS17880 | 3456671..3457174 | - | 504 | WP_003246050.1 | HK97 gp10 family phage protein | - |
ABU16_RS17885 | 3457171..3457533 | - | 363 | WP_003229925.1 | YqbH/XkdH family protein | - |
ABU16_RS17890 | 3457530..3457925 | - | 396 | WP_004398566.1 | DUF3199 family protein | - |
ABU16_RS17895 | 3457929..3458240 | - | 312 | WP_003229923.1 | YqbF domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | - | 3422797..3474287 | 51490 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 60 a.a. Molecular weight: 6739.19 Da Isoelectric Point: 8.0370
>T55149 WP_004398662.1 NZ_CP011882:3453284-3453463 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG
Download Length: 180 bp
>T55149 NZ_CP011882:3453284-3453463 [Bacillus subtilis]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG
Antitoxin
Download Length: 223 bp
>AT55149 NZ_CP011882:c3453609-3453387 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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