Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 3453284..3453609 Replicon chromosome
Accession NZ_CP011882
Organism Bacillus subtilis strain TO-A JPC

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag ABU16_RS17855 Protein ID WP_004398662.1
Coordinates 3453284..3453463 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 3453387..3453609 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ABU16_RS22070 3452510..3452647 - 138 WP_003229934.1 hypothetical protein -
ABU16_RS17850 3452689..3453138 - 450 WP_003229933.1 phage portal protein -
ABU16_RS17855 3453284..3453463 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- 3453387..3453609 - 223 NuclAT_0 - Antitoxin
- 3453387..3453609 - 223 NuclAT_0 - Antitoxin
- 3453387..3453609 - 223 NuclAT_0 - Antitoxin
- 3453387..3453609 - 223 NuclAT_0 - Antitoxin
ABU16_RS22520 3453843..3453932 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
ABU16_RS17860 3454186..3454629 - 444 WP_003229930.1 phage tail tube protein -
ABU16_RS17865 3454632..3456032 - 1401 WP_003229929.1 phage tail sheath family protein -
ABU16_RS17870 3456033..3456224 - 192 WP_010886574.1 hypothetical protein -
ABU16_RS17875 3456221..3456658 - 438 WP_003229927.1 hypothetical protein -
ABU16_RS17880 3456671..3457174 - 504 WP_003246050.1 HK97 gp10 family phage protein -
ABU16_RS17885 3457171..3457533 - 363 WP_003229925.1 YqbH/XkdH family protein -
ABU16_RS17890 3457530..3457925 - 396 WP_004398566.1 DUF3199 family protein -
ABU16_RS17895 3457929..3458240 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 3422797..3474287 51490


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T55149 WP_004398662.1 NZ_CP011882:3453284-3453463 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

>T55149 NZ_CP011882:3453284-3453463 [Bacillus subtilis]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG

Antitoxin


Download         Length: 223 bp

>AT55149 NZ_CP011882:c3453609-3453387 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References