Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-ratA/- |
Location | 2678240..2678565 | Replicon | chromosome |
Accession | NZ_CP011115 | ||
Organism | Bacillus subtilis KCTC 1028 = ATCC 6051a strain KCTC 1028 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | P54373 |
Locus tag | O7A_RS14185 | Protein ID | WP_004398662.1 |
Coordinates | 2678240..2678419 (+) | Length | 60 a.a. |
Antitoxin (RNA)
Gene name | ratA | ||
Locus tag | - | ||
Coordinates | 2678343..2678565 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
O7A_RS22880 | 2677466..2677603 | - | 138 | WP_003229934.1 | hypothetical protein | - |
O7A_RS14180 | 2677645..2678094 | - | 450 | WP_003229933.1 | phage portal protein | - |
O7A_RS14185 | 2678240..2678419 | + | 180 | WP_004398662.1 | type I toxin-antitoxin system toxin TxpA | Toxin |
- | 2678343..2678565 | - | 223 | NuclAT_0 | - | Antitoxin |
- | 2678343..2678565 | - | 223 | NuclAT_0 | - | Antitoxin |
- | 2678343..2678565 | - | 223 | NuclAT_0 | - | Antitoxin |
- | 2678343..2678565 | - | 223 | NuclAT_0 | - | Antitoxin |
O7A_RS23470 | 2678799..2678888 | + | 90 | WP_075058862.1 | type I toxin-antitoxin system toxin BsrH | - |
O7A_RS14190 | 2679142..2679585 | - | 444 | WP_003229930.1 | phage tail tube protein | - |
O7A_RS14195 | 2679588..2680988 | - | 1401 | WP_003229929.1 | phage tail sheath family protein | - |
O7A_RS14200 | 2680989..2681180 | - | 192 | WP_010886574.1 | hypothetical protein | - |
O7A_RS14205 | 2681177..2681614 | - | 438 | WP_003229927.1 | hypothetical protein | - |
O7A_RS14210 | 2681627..2682130 | - | 504 | WP_003246050.1 | HK97 gp10 family phage protein | - |
O7A_RS14215 | 2682127..2682489 | - | 363 | WP_003229925.1 | YqbH/XkdH family protein | - |
O7A_RS14220 | 2682486..2682881 | - | 396 | WP_004398566.1 | DUF3199 family protein | - |
O7A_RS14225 | 2682885..2683196 | - | 312 | WP_003229923.1 | YqbF domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | - | 2645490..2699243 | 53753 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 60 a.a. Molecular weight: 6739.19 Da Isoelectric Point: 8.0370
>T53446 WP_004398662.1 NZ_CP011115:2678240-2678419 [Bacillus subtilis KCTC 1028 = ATCC 6051a]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG
Download Length: 180 bp
>T53446 NZ_CP011115:2678240-2678419 [Bacillus subtilis KCTC 1028 = ATCC 6051a]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG
Antitoxin
Download Length: 223 bp
>AT53446 NZ_CP011115:c2678565-2678343 [Bacillus subtilis KCTC 1028 = ATCC 6051a]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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