52009

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2657733..2658058 Replicon chromosome
Accession NZ_CP010314
Organism Bacillus subtilis subsp. subtilis strain 3NA isolate 1970 (Michel and Millet)

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag RP72_RS14075 Protein ID WP_004398662.1
Coordinates 2657733..2657912 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2657836..2658058 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RP72_RS22770 2656959..2657096 - 138 WP_003229934.1 hypothetical protein -
RP72_RS14070 2657138..2657587 - 450 WP_003229933.1 phage portal protein -
RP72_RS14075 2657733..2657912 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- 2657836..2658058 - 223 NuclAT_0 - Antitoxin
- 2657836..2658058 - 223 NuclAT_0 - Antitoxin
- 2657836..2658058 - 223 NuclAT_0 - Antitoxin
- 2657836..2658058 - 223 NuclAT_0 - Antitoxin
RP72_RS23355 2658292..2658381 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
RP72_RS14080 2658635..2659078 - 444 WP_003229930.1 phage tail tube protein -
RP72_RS14085 2659081..2660481 - 1401 WP_003229929.1 phage tail sheath family protein -
RP72_RS14090 2660482..2660673 - 192 WP_010886574.1 hypothetical protein -
RP72_RS14095 2660670..2661107 - 438 WP_003229927.1 hypothetical protein -
RP72_RS14100 2661120..2661623 - 504 WP_003246050.1 HK97 gp10 family phage protein -
RP72_RS14105 2661620..2661982 - 363 WP_003229925.1 YqbH/XkdH family protein -
RP72_RS14110 2661979..2662374 - 396 WP_004398566.1 DUF3199 family protein -
RP72_RS14115 2662378..2662689 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2624983..2678736 53753


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T52009 WP_004398662.1 NZ_CP010314:2657733-2657912 [Bacillus subtilis subsp. subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

>T52009 NZ_CP010314:2657733-2657912 [Bacillus subtilis subsp. subtilis]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG

Antitoxin


Download         Length: 223 bp

>AT52009 NZ_CP010314:c2658058-2657836 [Bacillus subtilis subsp. subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References