Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) cjpT-cjrA/-
Location 35356..35839 Replicon plasmid pCj2
Accession NZ_CP010074
Organism Campylobacter jejuni subsp. jejuni strain 01-1512

Toxin (Protein)


Gene name cjpT Uniprot ID Q8GJA8
Locus tag PJ19_RS09860 Protein ID WP_011117588.1
Coordinates 35356..35760 (+) Length 135 a.a.

Antitoxin (RNA)


Gene name cjrA
Locus tag -
Coordinates 35762..35839 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PJ19_RS09810 31071..31415 + 345 WP_011117579.1 hypothetical protein -
PJ19_RS09815 31429..31737 + 309 WP_011117580.1 hypothetical protein -
PJ19_RS09820 31747..31968 + 222 WP_011799395.1 hypothetical protein -
PJ19_RS09825 31981..32376 + 396 WP_011117582.1 hypothetical protein -
PJ19_RS09830 32449..32859 + 411 WP_011117583.1 hypothetical protein -
PJ19_RS09835 32856..33287 + 432 WP_002815407.1 hypothetical protein -
PJ19_RS09840 33287..33589 + 303 WP_025443373.1 hypothetical protein -
PJ19_RS09845 33801..34166 + 366 WP_011117585.1 hypothetical protein -
PJ19_RS09850 34230..34565 + 336 WP_011117586.1 hypothetical protein -
PJ19_RS09855 34752..35114 + 363 WP_011117587.1 hypothetical protein -
PJ19_RS09860 35356..35760 + 405 WP_011117588.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
- 35762..35839 - 78 NuclAT_0 - Antitoxin
- 35762..35839 - 78 NuclAT_0 - Antitoxin
- 35762..35839 - 78 NuclAT_0 - Antitoxin
- 35762..35839 - 78 NuclAT_0 - Antitoxin
PJ19_RS09865 36006..36398 + 393 WP_043012974.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Non-Mobilizable plasmid - virB4 / Cjp54 / virB8 / virB9 / virB10 / virB11 / virD4 1..36604 36604


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(28-130)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15715.47 Da        Isoelectric Point: 10.5279

>T50343 WP_011117588.1 NZ_CP010074:35356-35760 [Campylobacter jejuni subsp. jejuni]
MQNEDLKFDEWNEVKKHIEKEKNKIVKKQKIYWIKIGKNIGSEIFGKGRVFARPVLVINVFYNGLFLGVPLSSKTKNKSG
KLYYKFTDEKGNSQVALLGQMKIFDNKRKITFESNVKNEDFILIKEKIKKNIID

Download         Length: 405 bp

>T50343 NZ_CP010074:35356-35760 [Campylobacter jejuni subsp. jejuni]
ATGCAAAATGAAGATTTGAAATTTGATGAATGGAATGAAGTTAAAAAACATATTGAAAAAGAAAAAAATAAAATTGTTAA
AAAACAAAAAATATATTGGATTAAAATTGGTAAAAATATAGGGAGTGAGATTTTTGGCAAAGGAAGGGTTTTTGCACGCC
CTGTTTTAGTAATTAATGTATTTTATAATGGTTTGTTTTTAGGAGTTCCTTTAAGTTCAAAAACAAAAAATAAAAGTGGT
AAGCTATATTATAAATTCACAGATGAAAAAGGAAATTCGCAAGTTGCACTTTTGGGGCAAATGAAAATTTTTGATAATAA
GAGAAAAATAACATTTGAAAGCAATGTTAAAAATGAAGATTTTATTTTAATAAAAGAAAAAATAAAAAAGAATATTATAG
ATTAA

Antitoxin


Download         Length: 78 bp

>AT50343 NZ_CP010074:c35839-35762 [Campylobacter jejuni subsp. jejuni]
TTGACTTCCTAAATGAAAGTTTAGCGAAGAATTGGCTTATCTTTTAGATAGGTTGCCCCGTCATAGAGCGGGGATAAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z8TNU2

Antitoxin

Download structure file

References