Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/VapC-StbC |
Location | 1536433..1537116 | Replicon | chromosome |
Accession | NZ_CP009790 | ||
Organism | Xylella fastidiosa strain U24d |
Toxin (Protein)
Gene name | vapC | Uniprot ID | Q9PD15 |
Locus tag | XFUD_RS07215 | Protein ID | WP_010894086.1 |
Coordinates | 1536433..1536861 (-) | Length | 143 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | XFUD_RS07220 | Protein ID | WP_042463183.1 |
Coordinates | 1536862..1537116 (-) | Length | 85 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
XFUD_RS07190 | 1532589..1533026 | + | 438 | WP_010894081.1 | DUF3277 family protein | - |
XFUD_RS07195 | 1533023..1533445 | + | 423 | WP_010894082.1 | hypothetical protein | - |
XFUD_RS07200 | 1533593..1535482 | + | 1890 | WP_010894084.1 | hypothetical protein | - |
XFUD_RS07205 | 1535809..1536057 | + | 249 | WP_042463681.1 | hypothetical protein | - |
XFUD_RS07210 | 1535942..1536294 | - | 353 | Protein_1295 | antitoxin | - |
XFUD_RS07215 | 1536433..1536861 | - | 429 | WP_010894086.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
XFUD_RS07220 | 1536862..1537116 | - | 255 | WP_042463183.1 | plasmid stabilization protein | Antitoxin |
XFUD_RS07225 | 1537228..1537998 | + | 771 | WP_010894088.1 | hypothetical protein | - |
XFUD_RS07230 | 1537998..1538315 | + | 318 | WP_010894089.1 | hypothetical protein | - |
XFUD_RS07235 | 1538312..1539142 | + | 831 | WP_010894090.1 | hypothetical protein | - |
XFUD_RS07240 | 1539139..1539780 | + | 642 | WP_010894091.1 | hypothetical protein | - |
XFUD_RS07245 | 1539777..1540130 | + | 354 | WP_010894092.1 | hypothetical protein | - |
XFUD_RS07250 | 1540186..1540479 | - | 294 | WP_004085592.1 | putative addiction module antidote protein | - |
XFUD_RS07255 | 1540482..1540778 | - | 297 | WP_010894094.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
XFUD_RS07260 | 1540970..1541189 | + | 220 | Protein_1305 | tail fiber protein | - |
XFUD_RS07265 | 1541379..1541825 | - | 447 | WP_031336674.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | - | 1514336..1540778 | 26442 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 143 a.a. Molecular weight: 15613.78 Da Isoelectric Point: 5.8629
>T49813 WP_010894086.1 NZ_CP009790:c1536861-1536433 [Xylella fastidiosa]
MIVLDTNVVSEAMKPEPDAAVRTWLNEQMSVTLYLSSVTLSELLFGIAVLPTSKRKDMLARTLDGLLDLFNERVLPFNTD
AARHYAELAVKARNSGRGFPTPDGYIAAIAASRGYIVASRDTSAYESSGVQVINPWQYSKQT
MIVLDTNVVSEAMKPEPDAAVRTWLNEQMSVTLYLSSVTLSELLFGIAVLPTSKRKDMLARTLDGLLDLFNERVLPFNTD
AARHYAELAVKARNSGRGFPTPDGYIAAIAASRGYIVASRDTSAYESSGVQVINPWQYSKQT
Download Length: 429 bp
>T49813 NZ_CP009790:c1536861-1536433 [Xylella fastidiosa]
ATGATTGTCTTGGATACCAATGTTGTTTCCGAAGCAATGAAACCCGAACCGGATGCAGCAGTCCGAACCTGGCTCAACGA
GCAGATGAGCGTCACGTTGTACCTATCCAGTGTGACGTTATCTGAACTGTTGTTTGGAATCGCAGTGTTGCCCACAAGTA
AACGCAAGGACATGTTGGCTCGAACCCTTGATGGCTTGCTTGATCTGTTCAATGAACGGGTGTTGCCGTTCAATACGGAC
GCGGCACGCCACTATGCCGAACTGGCAGTGAAAGCGAGAAACAGCGGGCGCGGCTTCCCCACACCGGATGGCTATATCGC
GGCAATTGCTGCATCACGAGGTTACATAGTGGCTTCCCGCGACACCTCAGCCTATGAGTCAAGTGGTGTGCAAGTCATCA
ATCCGTGGCAATACAGCAAACAAACATAG
ATGATTGTCTTGGATACCAATGTTGTTTCCGAAGCAATGAAACCCGAACCGGATGCAGCAGTCCGAACCTGGCTCAACGA
GCAGATGAGCGTCACGTTGTACCTATCCAGTGTGACGTTATCTGAACTGTTGTTTGGAATCGCAGTGTTGCCCACAAGTA
AACGCAAGGACATGTTGGCTCGAACCCTTGATGGCTTGCTTGATCTGTTCAATGAACGGGTGTTGCCGTTCAATACGGAC
GCGGCACGCCACTATGCCGAACTGGCAGTGAAAGCGAGAAACAGCGGGCGCGGCTTCCCCACACCGGATGGCTATATCGC
GGCAATTGCTGCATCACGAGGTTACATAGTGGCTTCCCGCGACACCTCAGCCTATGAGTCAAGTGGTGTGCAAGTCATCA
ATCCGTGGCAATACAGCAAACAAACATAG
Antitoxin
Download Length: 85 a.a. Molecular weight: 9607.93 Da Isoelectric Point: 6.4732
>AT49813 WP_042463183.1 NZ_CP009790:c1537116-1536862 [Xylella fastidiosa]
MAMLTVRNLPDEVHRALRVRAATHGRSTEAEVREILTNMVKPDERVRIGDALATLGREIGLNNEDFTTFDKVRDKTQAEP
MRFE
MAMLTVRNLPDEVHRALRVRAATHGRSTEAEVREILTNMVKPDERVRIGDALATLGREIGLNNEDFTTFDKVRDKTQAEP
MRFE
Download Length: 255 bp
>AT49813 NZ_CP009790:c1537116-1536862 [Xylella fastidiosa]
ATGGCCATGTTGACAGTGCGTAATTTGCCTGATGAAGTCCATCGAGCCTTGCGGGTTCGAGCCGCCACACACGGCCGCAG
TACAGAAGCAGAAGTACGTGAGATTTTAACGAACATGGTCAAGCCAGATGAGCGTGTTCGCATTGGCGATGCCTTGGCTA
CCCTGGGACGCGAGATCGGACTAAATAACGAGGATTTCACGACCTTTGATAAGGTGCGAGATAAGACGCAGGCCGAGCCA
ATGAGATTTGAATGA
ATGGCCATGTTGACAGTGCGTAATTTGCCTGATGAAGTCCATCGAGCCTTGCGGGTTCGAGCCGCCACACACGGCCGCAG
TACAGAAGCAGAAGTACGTGAGATTTTAACGAACATGGTCAAGCCAGATGAGCGTGTTCGCATTGGCGATGCCTTGGCTA
CCCTGGGACGCGAGATCGGACTAAATAACGAGGATTTCACGACCTTTGATAAGGTGCGAGATAAGACGCAGGCCGAGCCA
ATGAGATTTGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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