Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-ratA/- |
Location | 2651006..2651331 | Replicon | chromosome |
Accession | NZ_CP007800 | ||
Organism | Bacillus subtilis subsp. subtilis str. JH642 substr. AG174 strain JH642 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | P54373 |
Locus tag | BSUA_RS14125 | Protein ID | WP_004398662.1 |
Coordinates | 2651006..2651185 (+) | Length | 60 a.a. |
Antitoxin (RNA)
Gene name | ratA | ||
Locus tag | - | ||
Coordinates | 2651109..2651331 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BSUA_RS14115 | 2650232..2650369 | - | 138 | WP_003229934.1 | hypothetical protein | - |
BSUA_RS14120 | 2650411..2650860 | - | 450 | WP_003229933.1 | phage portal protein | - |
BSUA_RS14125 | 2651006..2651185 | + | 180 | WP_004398662.1 | type I toxin-antitoxin system toxin TxpA | Toxin |
- | 2651109..2651331 | - | 223 | NuclAT_0 | - | Antitoxin |
- | 2651109..2651331 | - | 223 | NuclAT_0 | - | Antitoxin |
- | 2651109..2651331 | - | 223 | NuclAT_0 | - | Antitoxin |
- | 2651109..2651331 | - | 223 | NuclAT_0 | - | Antitoxin |
BSUA_RS22850 | 2651565..2651654 | + | 90 | WP_075058862.1 | type I toxin-antitoxin system toxin BsrH | - |
BSUA_RS14130 | 2651908..2652351 | - | 444 | WP_003229930.1 | phage tail tube protein | - |
BSUA_RS14135 | 2652354..2653754 | - | 1401 | WP_003229929.1 | phage tail sheath family protein | - |
BSUA_RS14140 | 2653755..2653946 | - | 192 | WP_010886574.1 | hypothetical protein | - |
BSUA_RS14145 | 2653943..2654380 | - | 438 | WP_003229927.1 | hypothetical protein | - |
BSUA_RS14150 | 2654393..2654896 | - | 504 | WP_003246050.1 | HK97 gp10 family phage protein | - |
BSUA_RS14155 | 2654893..2655255 | - | 363 | WP_003229925.1 | YqbH/XkdH family protein | - |
BSUA_RS14160 | 2655252..2655647 | - | 396 | WP_004398566.1 | DUF3199 family protein | - |
BSUA_RS14165 | 2655651..2655962 | - | 312 | WP_003229923.1 | YqbF domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | - | 2625759..2675870 | 50111 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 60 a.a. Molecular weight: 6739.19 Da Isoelectric Point: 8.0370
>T47077 WP_004398662.1 NZ_CP007800:2651006-2651185 [Bacillus subtilis subsp. subtilis str. JH642 substr. AG174]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG
Download Length: 180 bp
>T47077 NZ_CP007800:2651006-2651185 [Bacillus subtilis subsp. subtilis str. JH642 substr. AG174]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG
Antitoxin
Download Length: 223 bp
>AT47077 NZ_CP007800:c2651331-2651109 [Bacillus subtilis subsp. subtilis str. JH642 substr. AG174]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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