Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-ratA/- |
Location | 2484391..2484716 | Replicon | chromosome |
Accession | NZ_CP005997 | ||
Organism | Bacillus subtilis TO-A |
Toxin (Protein)
Gene name | txpA | Uniprot ID | P54373 |
Locus tag | M036_RS12895 | Protein ID | WP_004398662.1 |
Coordinates | 2484391..2484570 (+) | Length | 60 a.a. |
Antitoxin (RNA)
Gene name | ratA | ||
Locus tag | - | ||
Coordinates | 2484494..2484716 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
M036_RS12885 | 2483617..2483754 | - | 138 | WP_003229934.1 | hypothetical protein | - |
M036_RS12890 | 2483796..2484245 | - | 450 | WP_003229933.1 | phage portal protein | - |
M036_RS12895 | 2484391..2484570 | + | 180 | WP_004398662.1 | type I toxin-antitoxin system toxin TxpA | Toxin |
- | 2484494..2484716 | - | 223 | NuclAT_0 | - | Antitoxin |
- | 2484494..2484716 | - | 223 | NuclAT_0 | - | Antitoxin |
- | 2484494..2484716 | - | 223 | NuclAT_0 | - | Antitoxin |
- | 2484494..2484716 | - | 223 | NuclAT_0 | - | Antitoxin |
M036_RS21720 | 2484950..2485039 | + | 90 | WP_075058862.1 | type I toxin-antitoxin system toxin BsrH | - |
M036_RS12900 | 2485293..2485736 | - | 444 | WP_003229930.1 | phage tail tube protein | - |
M036_RS12905 | 2485739..2487139 | - | 1401 | WP_003229929.1 | phage tail sheath family protein | - |
M036_RS12910 | 2487140..2487331 | - | 192 | WP_010886574.1 | hypothetical protein | - |
M036_RS12915 | 2487328..2487765 | - | 438 | WP_003229927.1 | hypothetical protein | - |
M036_RS12920 | 2487778..2488281 | - | 504 | WP_003246050.1 | HK97 gp10 family phage protein | - |
M036_RS12925 | 2488278..2488640 | - | 363 | WP_003229925.1 | YqbH/XkdH family protein | - |
M036_RS12930 | 2488637..2489032 | - | 396 | WP_004398566.1 | DUF3199 family protein | - |
M036_RS12935 | 2489036..2489347 | - | 312 | WP_003229923.1 | YqbF domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | - | 2453904..2505394 | 51490 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 60 a.a. Molecular weight: 6739.19 Da Isoelectric Point: 8.0370
>T45159 WP_004398662.1 NZ_CP005997:2484391-2484570 [Bacillus subtilis TO-A]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG
Download Length: 180 bp
>T45159 NZ_CP005997:2484391-2484570 [Bacillus subtilis TO-A]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG
Antitoxin
Download Length: 223 bp
>AT45159 NZ_CP005997:c2484716-2484494 [Bacillus subtilis TO-A]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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