Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-ratA/- |
Location | 2650453..2650778 | Replicon | chromosome |
Accession | NZ_AP024627 | ||
Organism | Bacillus subtilis strain BEST3136 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | P54373 |
Locus tag | K6J86_RS13870 | Protein ID | WP_004398662.1 |
Coordinates | 2650453..2650632 (+) | Length | 60 a.a. |
Antitoxin (RNA)
Gene name | ratA | ||
Locus tag | - | ||
Coordinates | 2650556..2650778 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
K6J86_RS13860 (2649679) | 2649679..2649816 | - | 138 | WP_003229934.1 | hypothetical protein | - |
K6J86_RS13865 (2649858) | 2649858..2650307 | - | 450 | WP_003229933.1 | phage portal protein | - |
K6J86_RS13870 (2650453) | 2650453..2650632 | + | 180 | WP_004398662.1 | type I toxin-antitoxin system toxin TxpA | Toxin |
- (2650556) | 2650556..2650778 | - | 223 | NuclAT_0 | - | Antitoxin |
- (2650556) | 2650556..2650778 | - | 223 | NuclAT_0 | - | Antitoxin |
- (2650556) | 2650556..2650778 | - | 223 | NuclAT_0 | - | Antitoxin |
- (2650556) | 2650556..2650778 | - | 223 | NuclAT_0 | - | Antitoxin |
K6J86_RS13875 (2651012) | 2651012..2651101 | + | 90 | WP_075058862.1 | type I toxin-antitoxin system toxin BsrH | - |
K6J86_RS13880 (2651355) | 2651355..2651798 | - | 444 | WP_003229930.1 | phage tail tube protein | - |
K6J86_RS13885 (2651801) | 2651801..2653201 | - | 1401 | WP_003229929.1 | phage tail sheath family protein | - |
K6J86_RS13890 (2653202) | 2653202..2653393 | - | 192 | WP_010886574.1 | hypothetical protein | - |
K6J86_RS13895 (2653390) | 2653390..2653827 | - | 438 | WP_003229927.1 | hypothetical protein | - |
K6J86_RS13900 (2653840) | 2653840..2654343 | - | 504 | WP_003246050.1 | HK97 gp10 family phage protein | - |
K6J86_RS13905 (2654340) | 2654340..2654702 | - | 363 | WP_003229925.1 | YqbH/XkdH family protein | - |
K6J86_RS13910 (2654699) | 2654699..2655094 | - | 396 | WP_004398566.1 | DUF3199 family protein | - |
K6J86_RS13915 (2655098) | 2655098..2655409 | - | 312 | WP_003229923.1 | YqbF domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | - | 2625206..2675317 | 50111 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 60 a.a. Molecular weight: 6739.19 Da Isoelectric Point: 8.0370
>T39118 WP_004398662.1 NZ_AP024627:2650453-2650632 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG
Download Length: 180 bp
>T39118 NZ_AP024627:2650453-2650632 [Bacillus subtilis]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG
Antitoxin
Download Length: 223 bp
>AT39118 NZ_AP024627:c2650778-2650556 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|