Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-ratA/- |
Location | 2644334..2644659 | Replicon | chromosome |
Accession | NZ_AP024625 | ||
Organism | Bacillus subtilis strain BEST3109 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | P54373 |
Locus tag | BsBEST3145_RS13865 | Protein ID | WP_004398662.1 |
Coordinates | 2644334..2644513 (+) | Length | 60 a.a. |
Antitoxin (RNA)
Gene name | ratA | ||
Locus tag | - | ||
Coordinates | 2644437..2644659 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BsBEST3145_RS13855 (2643560) | 2643560..2643697 | - | 138 | WP_003229934.1 | hypothetical protein | - |
BsBEST3145_RS13860 (2643739) | 2643739..2644188 | - | 450 | WP_003229933.1 | phage portal protein | - |
BsBEST3145_RS13865 (2644334) | 2644334..2644513 | + | 180 | WP_004398662.1 | type I toxin-antitoxin system toxin TxpA | Toxin |
- (2644437) | 2644437..2644659 | - | 223 | NuclAT_0 | - | Antitoxin |
- (2644437) | 2644437..2644659 | - | 223 | NuclAT_0 | - | Antitoxin |
- (2644437) | 2644437..2644659 | - | 223 | NuclAT_0 | - | Antitoxin |
- (2644437) | 2644437..2644659 | - | 223 | NuclAT_0 | - | Antitoxin |
BsBEST3145_RS13870 (2644893) | 2644893..2644982 | + | 90 | WP_075058862.1 | type I toxin-antitoxin system toxin BsrH | - |
BsBEST3145_RS13875 (2645236) | 2645236..2645679 | - | 444 | WP_003229930.1 | phage tail tube protein | - |
BsBEST3145_RS13880 (2645682) | 2645682..2647082 | - | 1401 | WP_003229929.1 | phage tail sheath family protein | - |
BsBEST3145_RS13885 (2647083) | 2647083..2647274 | - | 192 | WP_010886574.1 | hypothetical protein | - |
BsBEST3145_RS13890 (2647271) | 2647271..2647708 | - | 438 | WP_003229927.1 | hypothetical protein | - |
BsBEST3145_RS13895 (2647721) | 2647721..2648224 | - | 504 | WP_003246050.1 | HK97 gp10 family phage protein | - |
BsBEST3145_RS13900 (2648221) | 2648221..2648583 | - | 363 | WP_003229925.1 | YqbH/XkdH family protein | - |
BsBEST3145_RS13905 (2648580) | 2648580..2648975 | - | 396 | WP_004398566.1 | DUF3199 family protein | - |
BsBEST3145_RS13910 (2648979) | 2648979..2649290 | - | 312 | WP_003229923.1 | YqbF domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | - | 2613847..2665337 | 51490 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 60 a.a. Molecular weight: 6739.19 Da Isoelectric Point: 8.0370
>T39072 WP_004398662.1 NZ_AP024625:2644334-2644513 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG
Download Length: 180 bp
>T39072 NZ_AP024625:2644334-2644513 [Bacillus subtilis]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG
Antitoxin
Download Length: 223 bp
>AT39072 NZ_AP024625:c2644659-2644437 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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