39003

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2657407..2657732 Replicon chromosome
Accession NZ_AP024622
Organism Bacillus subtilis strain BEST3096

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag K6K01_RS13920 Protein ID WP_004398662.1
Coordinates 2657407..2657586 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2657510..2657732 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6K01_RS13910 (2656633) 2656633..2656770 - 138 WP_003229934.1 hypothetical protein -
K6K01_RS13915 (2656812) 2656812..2657261 - 450 WP_003229933.1 phage portal protein -
K6K01_RS13920 (2657407) 2657407..2657586 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- (2657510) 2657510..2657732 - 223 NuclAT_0 - Antitoxin
- (2657510) 2657510..2657732 - 223 NuclAT_0 - Antitoxin
- (2657510) 2657510..2657732 - 223 NuclAT_0 - Antitoxin
- (2657510) 2657510..2657732 - 223 NuclAT_0 - Antitoxin
K6K01_RS13925 (2657966) 2657966..2658055 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
K6K01_RS13930 (2658309) 2658309..2658752 - 444 WP_003229930.1 phage tail tube protein -
K6K01_RS13935 (2658755) 2658755..2660155 - 1401 WP_003229929.1 phage tail sheath family protein -
K6K01_RS13940 (2660156) 2660156..2660347 - 192 WP_010886574.1 hypothetical protein -
K6K01_RS13945 (2660344) 2660344..2660781 - 438 WP_003229927.1 hypothetical protein -
K6K01_RS13950 (2660794) 2660794..2661297 - 504 WP_003246050.1 HK97 gp10 family phage protein -
K6K01_RS13955 (2661294) 2661294..2661656 - 363 WP_003229925.1 YqbH/XkdH family protein -
K6K01_RS13960 (2661653) 2661653..2662048 - 396 WP_004398566.1 DUF3199 family protein -
K6K01_RS13965 (2662052) 2662052..2662363 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2626920..2678410 51490


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T39003 WP_004398662.1 NZ_AP024622:2657407-2657586 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

>T39003 NZ_AP024622:2657407-2657586 [Bacillus subtilis]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG

Antitoxin


Download         Length: 223 bp

>AT39003 NZ_AP024622:c2657732-2657510 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References