Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2673540..2673865 Replicon chromosome
Accession NZ_AP019714
Organism Bacillus subtilis subsp. subtilis strain NBRC 13719

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag FNP71_RS14215 Protein ID WP_004398662.1
Coordinates 2673540..2673719 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2673643..2673865 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNP71_RS14205 2672766..2672903 - 138 WP_003229934.1 hypothetical protein -
FNP71_RS14210 2672945..2673394 - 450 WP_003229933.1 phage portal protein -
FNP71_RS14215 2673540..2673719 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- 2673643..2673865 - 223 NuclAT_0 - Antitoxin
- 2673643..2673865 - 223 NuclAT_0 - Antitoxin
- 2673643..2673865 - 223 NuclAT_0 - Antitoxin
- 2673643..2673865 - 223 NuclAT_0 - Antitoxin
FNP71_RS14220 2674099..2674188 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
FNP71_RS14225 2674442..2674885 - 444 WP_003229930.1 phage tail tube protein -
FNP71_RS14230 2674888..2676288 - 1401 WP_003229929.1 phage tail sheath family protein -
FNP71_RS14235 2676289..2676480 - 192 WP_010886574.1 hypothetical protein -
FNP71_RS14240 2676477..2676914 - 438 WP_003229927.1 hypothetical protein -
FNP71_RS14245 2676927..2677430 - 504 WP_003246050.1 HK97 gp10 family phage protein -
FNP71_RS14250 2677427..2677789 - 363 WP_003229925.1 YqbH/XkdH family protein -
FNP71_RS14255 2677786..2678181 - 396 WP_004398566.1 DUF3199 family protein -
FNP71_RS14260 2678185..2678496 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2632843..2694543 61700


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T32948 WP_004398662.1 NZ_AP019714:2673540-2673719 [Bacillus subtilis subsp. subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

>T32948 NZ_AP019714:2673540-2673719 [Bacillus subtilis subsp. subtilis]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG

Antitoxin


Download         Length: 223 bp

>AT32948 NZ_AP019714:c2673865-2673643 [Bacillus subtilis subsp. subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References