Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | TscAT/- |
Location | 2162147..2162625 | Replicon | chromosome |
Accession | NZ_AP019542 | ||
Organism | Staphylococcus aureus strain KG-03 |
Toxin (Protein)
Gene name | TscT | Uniprot ID | A0A0H3K0C1 |
Locus tag | GDK21_RS11000 | Protein ID | WP_001078344.1 |
Coordinates | 2162147..2162473 (-) | Length | 109 a.a. |
Antitoxin (Protein)
Gene name | TscA | Uniprot ID | - |
Locus tag | GDK21_RS11005 | Protein ID | WP_025175789.1 |
Coordinates | 2162476..2162625 (-) | Length | 50 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
GDK21_RS10975 | 2157371..2157712 | - | 342 | WP_001190615.1 | hypothetical protein | - |
GDK21_RS10980 | 2158162..2158803 | - | 642 | WP_001047698.1 | hypothetical protein | - |
GDK21_RS10985 | 2158800..2159180 | - | 381 | WP_000356942.1 | hypothetical protein | - |
GDK21_RS10990 | 2159490..2161199 | - | 1710 | WP_000447473.1 | DUF927 domain-containing protein | - |
GDK21_RS10995 | 2161213..2162082 | - | 870 | WP_152064758.1 | primase alpha helix C-terminal domain-containing protein | - |
GDK21_RS11000 | 2162147..2162473 | - | 327 | WP_001078344.1 | DUF1474 family protein | Toxin |
GDK21_RS11005 | 2162476..2162625 | - | 150 | WP_025175789.1 | hypothetical protein | Antitoxin |
GDK21_RS11010 | 2162678..2162824 | - | 147 | WP_000784885.1 | hypothetical protein | - |
GDK21_RS11015 | 2162821..2163138 | - | 318 | WP_000481967.1 | helix-turn-helix domain-containing protein | - |
GDK21_RS11020 | 2163143..2163361 | - | 219 | WP_000153640.1 | helix-turn-helix transcriptional regulator | - |
GDK21_RS11025 | 2163534..2164208 | + | 675 | WP_000620857.1 | helix-turn-helix transcriptional regulator | - |
GDK21_RS11030 | 2164222..2165394 | + | 1173 | WP_000179343.1 | site-specific integrase | - |
GDK21_RS11035 | 2165463..2167079 | - | 1617 | WP_000240642.1 | chaperonin GroEL | - |
GDK21_RS11040 | 2167155..2167439 | - | 285 | WP_000917289.1 | co-chaperone GroES | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | map / hlb / scn / chp / sak / see / hlb / sell / sec / tsst-1 / groEL | 2096150..2167439 | 71289 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 109 a.a. Molecular weight: 12968.26 Da Isoelectric Point: 4.3050
>T32702 WP_001078344.1 NZ_AP019542:c2162473-2162147 [Staphylococcus aureus]
MNREIKDLFSDLKLLKDSFEDLKDSNGWHFDELYPYEPNHVLNKDELIGEGFSYHERRIHNNQMFDLFHLYIEQFDNIIE
KFYEIEKASSENFGEESDDAKNSIKVAE
MNREIKDLFSDLKLLKDSFEDLKDSNGWHFDELYPYEPNHVLNKDELIGEGFSYHERRIHNNQMFDLFHLYIEQFDNIIE
KFYEIEKASSENFGEESDDAKNSIKVAE
Download Length: 327 bp
>T32702 NZ_AP019542:c2162473-2162147 [Staphylococcus aureus]
ATGAATCGGGAAATTAAAGATTTATTTAGCGATTTAAAGTTGTTGAAAGATAGTTTTGAGGATTTAAAGGATAGTAATGG
TTGGCATTTTGATGAGCTATATCCATATGAACCAAATCATGTCTTAAATAAAGATGAATTAATTGGAGAGGGATTTTCTT
ATCATGAGAGACGTATTCACAATAATCAAATGTTTGATTTATTCCATCTCTATATAGAGCAGTTCGATAATATTATCGAA
AAGTTTTATGAAATAGAAAAAGCATCATCTGAGAACTTTGGCGAGGAATCAGATGACGCAAAGAATTCAATAAAAGTAGC
AGAGTAA
ATGAATCGGGAAATTAAAGATTTATTTAGCGATTTAAAGTTGTTGAAAGATAGTTTTGAGGATTTAAAGGATAGTAATGG
TTGGCATTTTGATGAGCTATATCCATATGAACCAAATCATGTCTTAAATAAAGATGAATTAATTGGAGAGGGATTTTCTT
ATCATGAGAGACGTATTCACAATAATCAAATGTTTGATTTATTCCATCTCTATATAGAGCAGTTCGATAATATTATCGAA
AAGTTTTATGAAATAGAAAAAGCATCATCTGAGAACTTTGGCGAGGAATCAGATGACGCAAAGAATTCAATAAAAGTAGC
AGAGTAA
Antitoxin
Download Length: 50 a.a. Molecular weight: 5822.52 Da Isoelectric Point: 4.4876
>AT32702 WP_025175789.1 NZ_AP019542:c2162625-2162476 [Staphylococcus aureus]
VNNLESYEHTEYVNGIEVVSEISREKHLELIMKWCAQELKNNFQLEKGE
VNNLESYEHTEYVNGIEVVSEISREKHLELIMKWCAQELKNNFQLEKGE
Download Length: 150 bp
>AT32702 NZ_AP019542:c2162625-2162476 [Staphylococcus aureus]
GTGAATAATTTGGAAAGTTATGAACACACAGAATATGTTAATGGTATTGAAGTGGTTTCAGAGATCAGTCGTGAAAAGCA
CTTAGAATTGATAATGAAATGGTGCGCACAAGAATTAAAGAATAATTTTCAATTAGAGAAAGGAGAATAA
GTGAATAATTTGGAAAGTTATGAACACACAGAATATGTTAATGGTATTGAAGTGGTTTCAGAGATCAGTCGTGAAAAGCA
CTTAGAATTGATAATGAAATGGTGCGCACAAGAATTAAAGAATAATTTTCAATTAGAGAAAGGAGAATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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