30556

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2510032..2510357 Replicon chromosome
Accession NZ_AP012496
Organism Bacillus subtilis BEST7003

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag BEST7003_RS12495 Protein ID WP_004398662.1
Coordinates 2510032..2510211 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2510135..2510357 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BEST7003_RS20870 2509258..2509395 - 138 WP_003229934.1 hypothetical protein -
BEST7003_RS12490 2509437..2509886 - 450 WP_003229933.1 phage portal protein -
BEST7003_RS12495 2510032..2510211 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- 2510135..2510357 - 223 NuclAT_0 - Antitoxin
- 2510135..2510357 - 223 NuclAT_0 - Antitoxin
- 2510135..2510357 - 223 NuclAT_0 - Antitoxin
- 2510135..2510357 - 223 NuclAT_0 - Antitoxin
BEST7003_RS21840 2510591..2510680 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
BEST7003_RS12500 2510934..2511377 - 444 WP_003229930.1 phage tail tube protein -
BEST7003_RS12505 2511380..2512780 - 1401 WP_003229929.1 phage tail sheath family protein -
BEST7003_RS12510 2512781..2512972 - 192 WP_010886574.1 hypothetical protein -
BEST7003_RS12515 2512969..2513406 - 438 WP_003229927.1 hypothetical protein -
BEST7003_RS12520 2513419..2513922 - 504 WP_003246050.1 HK97 gp10 family phage protein -
BEST7003_RS12525 2513919..2514281 - 363 WP_003229925.1 YqbH/XkdH family protein -
BEST7003_RS12530 2514278..2514673 - 396 WP_004398566.1 DUF3199 family protein -
BEST7003_RS12535 2514677..2514988 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2479545..2534896 55351


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T30556 WP_004398662.1 NZ_AP012496:2510032-2510211 [Bacillus subtilis BEST7003]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

>T30556 NZ_AP012496:2510032-2510211 [Bacillus subtilis BEST7003]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG

Antitoxin


Download         Length: 223 bp

>AT30556 NZ_AP012496:c2510357-2510135 [Bacillus subtilis BEST7003]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References