Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2496094..2496419 Replicon chromosome
Accession NC_022898
Organism Bacillus subtilis PY79

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag U712_RS12445 Protein ID WP_004398662.1
Coordinates 2496094..2496273 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2496197..2496419 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
U712_RS20725 2495320..2495457 - 138 WP_003229934.1 hypothetical protein -
U712_RS12440 2495499..2495948 - 450 WP_003229933.1 phage portal protein -
U712_RS12445 2496094..2496273 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- 2496197..2496419 - 223 NuclAT_0 - Antitoxin
- 2496197..2496419 - 223 NuclAT_0 - Antitoxin
- 2496197..2496419 - 223 NuclAT_0 - Antitoxin
- 2496197..2496419 - 223 NuclAT_0 - Antitoxin
U712_RS21290 2496653..2496742 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
U712_RS12450 2496996..2497439 - 444 WP_003229930.1 phage tail tube protein -
U712_RS12455 2497442..2498842 - 1401 WP_003229929.1 phage tail sheath family protein -
U712_RS12460 2498843..2499034 - 192 WP_010886574.1 hypothetical protein -
U712_RS12465 2499031..2499468 - 438 WP_003229927.1 hypothetical protein -
U712_RS12470 2499481..2499984 - 504 WP_003246050.1 HK97 gp10 family phage protein -
U712_RS12475 2499981..2500343 - 363 WP_003229925.1 YqbH/XkdH family protein -
U712_RS12480 2500340..2500735 - 396 WP_004398566.1 DUF3199 family protein -
U712_RS12485 2500739..2501050 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2463344..2517097 53753


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T30342 WP_004398662.1 NC_022898:2496094-2496273 [Bacillus subtilis PY79]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

>T30342 NC_022898:2496094-2496273 [Bacillus subtilis PY79]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG

Antitoxin


Download         Length: 223 bp

>AT30342 NC_022898:c2496419-2496197 [Bacillus subtilis PY79]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References