Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2726766..2727091 Replicon chromosome
Accession NZ_OX419580
Organism Bacillus subtilis isolate NRS6116

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag KJP60_RS14470 Protein ID WP_004398662.1
Coordinates 2726766..2726945 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2726869..2727091 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJP60_RS14460 (2725992) 2725992..2726129 - 138 WP_003229934.1 hypothetical protein -
KJP60_RS14465 (2726171) 2726171..2726620 - 450 WP_003229933.1 phage portal protein -
KJP60_RS14470 (2726766) 2726766..2726945 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- (2726869) 2726869..2727091 - 223 NuclAT_0 - Antitoxin
- (2726869) 2726869..2727091 - 223 NuclAT_0 - Antitoxin
- (2726869) 2726869..2727091 - 223 NuclAT_0 - Antitoxin
- (2726869) 2726869..2727091 - 223 NuclAT_0 - Antitoxin
KJP60_RS14475 (2727325) 2727325..2727414 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
KJP60_RS14480 (2727668) 2727668..2728111 - 444 WP_003229930.1 phage tail tube protein -
KJP60_RS14485 (2728114) 2728114..2729514 - 1401 WP_003229929.1 phage tail sheath family protein -
KJP60_RS14490 (2729515) 2729515..2729706 - 192 WP_010886574.1 hypothetical protein -
KJP60_RS14495 (2729703) 2729703..2730140 - 438 WP_003229927.1 hypothetical protein -
KJP60_RS14500 (2730153) 2730153..2730656 - 504 WP_003246050.1 HK97 gp10 family phage protein -
KJP60_RS14505 (2730653) 2730653..2731015 - 363 WP_003229925.1 YqbH/XkdH family protein -
KJP60_RS14510 (2731012) 2731012..2731407 - 396 WP_004398566.1 DUF3199 family protein -
KJP60_RS14515 (2731411) 2731411..2731722 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2694016..2747769 53753


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T296945 WP_004398662.1 NZ_OX419580:2726766-2726945 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

Antitoxin


Download         Length: 223 bp

>AT296945 NZ_OX419580:c2727091-2726869 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References