Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2565723..2566048 Replicon chromosome
Accession NZ_OX419575
Organism Bacillus subtilis isolate NRS6121

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag KJP52_RS13250 Protein ID WP_004398662.1
Coordinates 2565723..2565902 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2565826..2566048 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJP52_RS13240 (2564949) 2564949..2565086 - 138 WP_003229934.1 hypothetical protein -
KJP52_RS13245 (2565128) 2565128..2565577 - 450 WP_003229933.1 phage portal protein -
KJP52_RS13250 (2565723) 2565723..2565902 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- (2565826) 2565826..2566048 - 223 NuclAT_0 - Antitoxin
- (2565826) 2565826..2566048 - 223 NuclAT_0 - Antitoxin
- (2565826) 2565826..2566048 - 223 NuclAT_0 - Antitoxin
- (2565826) 2565826..2566048 - 223 NuclAT_0 - Antitoxin
KJP52_RS13255 (2566282) 2566282..2566371 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
KJP52_RS13260 (2566625) 2566625..2567068 - 444 WP_003229930.1 phage tail tube protein -
KJP52_RS13265 (2567071) 2567071..2568471 - 1401 WP_003229929.1 phage tail sheath family protein -
KJP52_RS13270 (2568472) 2568472..2568663 - 192 WP_010886574.1 hypothetical protein -
KJP52_RS13275 (2568660) 2568660..2569097 - 438 WP_003229927.1 hypothetical protein -
KJP52_RS13280 (2569110) 2569110..2569613 - 504 WP_003246050.1 HK97 gp10 family phage protein -
KJP52_RS13285 (2569610) 2569610..2569972 - 363 WP_003229925.1 YqbH/XkdH family protein -
KJP52_RS13290 (2569969) 2569969..2570364 - 396 WP_004398566.1 DUF3199 family protein -
KJP52_RS13295 (2570368) 2570368..2570679 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2532973..2586726 53753


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T296892 WP_004398662.1 NZ_OX419575:2565723-2565902 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

Antitoxin


Download         Length: 223 bp

>AT296892 NZ_OX419575:c2566048-2565826 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References