Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2723554..2723879 Replicon chromosome
Accession NZ_OX419569
Organism Bacillus subtilis isolate NRS6118

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag KJP55_RS14370 Protein ID WP_004398662.1
Coordinates 2723554..2723733 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2723657..2723879 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJP55_RS14360 (2722780) 2722780..2722917 - 138 WP_003229934.1 hypothetical protein -
KJP55_RS14365 (2722959) 2722959..2723408 - 450 WP_003229933.1 phage portal protein -
KJP55_RS14370 (2723554) 2723554..2723733 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- (2723657) 2723657..2723879 - 223 NuclAT_0 - Antitoxin
- (2723657) 2723657..2723879 - 223 NuclAT_0 - Antitoxin
- (2723657) 2723657..2723879 - 223 NuclAT_0 - Antitoxin
- (2723657) 2723657..2723879 - 223 NuclAT_0 - Antitoxin
KJP55_RS14375 (2724113) 2724113..2724202 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
KJP55_RS14380 (2724456) 2724456..2724899 - 444 WP_003229930.1 phage tail tube protein -
KJP55_RS14385 (2724902) 2724902..2726302 - 1401 WP_003229929.1 phage tail sheath family protein -
KJP55_RS14390 (2726303) 2726303..2726494 - 192 WP_010886574.1 hypothetical protein -
KJP55_RS14395 (2726491) 2726491..2726928 - 438 WP_003229927.1 hypothetical protein -
KJP55_RS14400 (2726941) 2726941..2727444 - 504 WP_003246050.1 HK97 gp10 family phage protein -
KJP55_RS14405 (2727441) 2727441..2727803 - 363 WP_003229925.1 YqbH/XkdH family protein -
KJP55_RS14410 (2727800) 2727800..2728195 - 396 WP_004398566.1 DUF3199 family protein -
KJP55_RS14415 (2728199) 2728199..2728510 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2682857..2744557 61700


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T296861 WP_004398662.1 NZ_OX419569:2723554-2723733 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

Antitoxin


Download         Length: 223 bp

>AT296861 NZ_OX419569:c2723879-2723657 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References