Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2563876..2564201 Replicon chromosome
Accession NZ_OX419567
Organism Bacillus subtilis isolate NRS6107

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag KJP42_RS13220 Protein ID WP_004398662.1
Coordinates 2563876..2564055 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2563979..2564201 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJP42_RS13210 (2563102) 2563102..2563239 - 138 WP_003229934.1 hypothetical protein -
KJP42_RS13215 (2563281) 2563281..2563730 - 450 WP_003229933.1 phage portal protein -
KJP42_RS13220 (2563876) 2563876..2564055 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- (2563979) 2563979..2564201 - 223 NuclAT_0 - Antitoxin
- (2563979) 2563979..2564201 - 223 NuclAT_0 - Antitoxin
- (2563979) 2563979..2564201 - 223 NuclAT_0 - Antitoxin
- (2563979) 2563979..2564201 - 223 NuclAT_0 - Antitoxin
KJP42_RS13225 (2564435) 2564435..2564524 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
KJP42_RS13230 (2564778) 2564778..2565221 - 444 WP_003229930.1 phage tail tube protein -
KJP42_RS13235 (2565224) 2565224..2566624 - 1401 WP_003229929.1 phage tail sheath family protein -
KJP42_RS13240 (2566625) 2566625..2566816 - 192 WP_010886574.1 hypothetical protein -
KJP42_RS13245 (2566813) 2566813..2567250 - 438 WP_003229927.1 hypothetical protein -
KJP42_RS13250 (2567263) 2567263..2567766 - 504 WP_003246050.1 HK97 gp10 family phage protein -
KJP42_RS13255 (2567763) 2567763..2568125 - 363 WP_003229925.1 YqbH/XkdH family protein -
KJP42_RS13260 (2568122) 2568122..2568517 - 396 WP_004398566.1 DUF3199 family protein -
KJP42_RS13265 (2568521) 2568521..2568832 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2531126..2584879 53753


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T296840 WP_004398662.1 NZ_OX419567:2563876-2564055 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

Antitoxin


Download         Length: 223 bp

>AT296840 NZ_OX419567:c2564201-2563979 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References