Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2639155..2639480 Replicon chromosome
Accession NZ_OX419563
Organism Bacillus subtilis isolate NRS6153

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag KJP66_RS13760 Protein ID WP_004398662.1
Coordinates 2639155..2639334 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2639258..2639480 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJP66_RS13750 (2638381) 2638381..2638518 - 138 WP_003229934.1 hypothetical protein -
KJP66_RS13755 (2638560) 2638560..2639009 - 450 WP_003229933.1 phage portal protein -
KJP66_RS13760 (2639155) 2639155..2639334 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- (2639258) 2639258..2639480 - 223 NuclAT_0 - Antitoxin
- (2639258) 2639258..2639480 - 223 NuclAT_0 - Antitoxin
- (2639258) 2639258..2639480 - 223 NuclAT_0 - Antitoxin
- (2639258) 2639258..2639480 - 223 NuclAT_0 - Antitoxin
KJP66_RS13765 (2639714) 2639714..2639803 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
KJP66_RS13770 (2640057) 2640057..2640500 - 444 WP_003229930.1 phage tail tube protein -
KJP66_RS13775 (2640503) 2640503..2641903 - 1401 WP_003229929.1 phage tail sheath family protein -
KJP66_RS13780 (2641904) 2641904..2642095 - 192 WP_010886574.1 hypothetical protein -
KJP66_RS13785 (2642092) 2642092..2642529 - 438 WP_003229927.1 hypothetical protein -
KJP66_RS13790 (2642542) 2642542..2643045 - 504 WP_003246050.1 HK97 gp10 family phage protein -
KJP66_RS13795 (2643042) 2643042..2643404 - 363 WP_003229925.1 YqbH/XkdH family protein -
KJP66_RS13800 (2643401) 2643401..2643796 - 396 WP_004398566.1 DUF3199 family protein -
KJP66_RS13805 (2643800) 2643800..2644111 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2606405..2668599 62194


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T296813 WP_004398662.1 NZ_OX419563:2639155-2639334 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

Antitoxin


Download         Length: 223 bp

>AT296813 NZ_OX419563:c2639480-2639258 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References