Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2567230..2567555 Replicon chromosome
Accession NZ_OX419551
Organism Bacillus subtilis isolate NRS6190

Toxin (Protein)


Gene name txpA Uniprot ID P54373
Locus tag KJP53_RS13240 Protein ID WP_004398662.1
Coordinates 2567230..2567409 (+) Length 60 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2567333..2567555 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJP53_RS13230 (2566456) 2566456..2566593 - 138 WP_003229934.1 hypothetical protein -
KJP53_RS13235 (2566635) 2566635..2567084 - 450 WP_003229933.1 phage portal protein -
KJP53_RS13240 (2567230) 2567230..2567409 + 180 WP_004398662.1 type I toxin-antitoxin system toxin TxpA Toxin
- (2567333) 2567333..2567555 - 223 NuclAT_0 - Antitoxin
- (2567333) 2567333..2567555 - 223 NuclAT_0 - Antitoxin
- (2567333) 2567333..2567555 - 223 NuclAT_0 - Antitoxin
- (2567333) 2567333..2567555 - 223 NuclAT_0 - Antitoxin
KJP53_RS13245 (2567789) 2567789..2567878 + 90 WP_075058862.1 type I toxin-antitoxin system toxin BsrH -
KJP53_RS13250 (2568132) 2568132..2568575 - 444 WP_003229930.1 phage tail tube protein -
KJP53_RS13255 (2568578) 2568578..2569978 - 1401 WP_003229929.1 phage tail sheath family protein -
KJP53_RS13260 (2569979) 2569979..2570170 - 192 WP_010886574.1 hypothetical protein -
KJP53_RS13265 (2570167) 2570167..2570604 - 438 WP_003229927.1 hypothetical protein -
KJP53_RS13270 (2570617) 2570617..2571120 - 504 WP_003246050.1 HK97 gp10 family phage protein -
KJP53_RS13275 (2571117) 2571117..2571479 - 363 WP_003229925.1 YqbH/XkdH family protein -
KJP53_RS13280 (2571476) 2571476..2571871 - 396 WP_004398566.1 DUF3199 family protein -
KJP53_RS13285 (2571875) 2571875..2572186 - 312 WP_003229923.1 YqbF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2534480..2588233 53753


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6739.19 Da        Isoelectric Point: 8.0370

>T296758 WP_004398662.1 NZ_OX419551:2567230-2567409 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Download         Length: 180 bp

Antitoxin


Download         Length: 223 bp

>AT296758 NZ_OX419551:c2567555-2567333 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A164X333

Antitoxin

Download structure file

References