Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/- |
Location | 2117095..2117518 | Replicon | chromosome |
Accession | NZ_LT598688 | ||
Organism | Staphylococcus aureus isolate Sa_Newman_UoM |
Toxin (Protein)
Gene name | higB | Uniprot ID | A0A5S9I4Y6 |
Locus tag | BN8422_RS10985 | Protein ID | WP_001065091.1 |
Coordinates | 2117267..2117518 (-) | Length | 84 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | A0A0E0VQM8 |
Locus tag | BN8422_RS10980 | Protein ID | WP_000028422.1 |
Coordinates | 2117095..2117277 (-) | Length | 61 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BN8422_RS10935 | 2112481..2114142 | - | 1662 | WP_000625088.1 | terminase large subunit | - |
BN8422_RS10940 | 2114139..2114483 | - | 345 | WP_000402904.1 | hypothetical protein | - |
BN8422_RS10945 | 2114613..2114912 | - | 300 | WP_000988336.1 | HNH endonuclease | - |
BN8422_RS10950 | 2115144..2115560 | - | 417 | WP_000590122.1 | hypothetical protein | - |
BN8422_RS10955 | 2115588..2115788 | - | 201 | WP_000265043.1 | DUF1514 family protein | - |
BN8422_RS10960 | 2115788..2115937 | - | 150 | WP_000595265.1 | transcriptional activator RinB | - |
BN8422_RS10965 | 2115934..2116320 | - | 387 | WP_000592210.1 | hypothetical protein | - |
BN8422_RS10970 | 2116317..2116523 | - | 207 | WP_000195803.1 | DUF1381 domain-containing protein | - |
BN8422_RS10975 | 2116560..2117102 | - | 543 | WP_000185659.1 | dUTP pyrophosphatase | - |
BN8422_RS10980 | 2117095..2117277 | - | 183 | WP_000028422.1 | hypothetical protein | Antitoxin |
BN8422_RS10985 | 2117267..2117518 | - | 252 | WP_001065091.1 | DUF1024 family protein | Toxin |
BN8422_RS15840 | 2117511..2117678 | - | 168 | WP_001624242.1 | hypothetical protein | - |
BN8422_RS10990 | 2117690..2117932 | - | 243 | WP_000131366.1 | hypothetical protein | - |
BN8422_RS10995 | 2117936..2118304 | - | 369 | WP_000101274.1 | hypothetical protein | - |
BN8422_RS11000 | 2118317..2118721 | - | 405 | WP_000401960.1 | RusA family crossover junction endodeoxyribonuclease | - |
BN8422_RS11005 | 2118730..2118948 | - | 219 | WP_000338530.1 | hypothetical protein | - |
BN8422_RS11010 | 2118955..2119839 | - | 885 | WP_000148316.1 | DnaD domain protein | - |
BN8422_RS11015 | 2119869..2120339 | - | 471 | WP_000934764.1 | single-stranded DNA-binding protein | - |
BN8422_RS11020 | 2120340..2120957 | - | 618 | WP_071621397.1 | MBL fold metallo-hydrolase | - |
BN8422_RS11025 | 2121038..2121958 | - | 921 | WP_000138472.1 | recombinase RecT | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | scn / chp / sak / sea / hlb / groEL | 2089428..2146378 | 56950 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A5S9I4Y6 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0E0VQM8 |