Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | parDE/RelE-RHH |
Location | 1986..2533 | Replicon | plasmid 2 |
Accession | NZ_LR898869 | ||
Organism | Escherichia coli isolate MSB1_1D-sc-2280324 |
Toxin (Protein)
Gene name | parE | Uniprot ID | E9LLH3 |
Locus tag | JMX26_RS22005 | Protein ID | WP_000969996.1 |
Coordinates | 2252..2533 (+) | Length | 94 a.a. |
Antitoxin (Protein)
Gene name | parD | Uniprot ID | K4JYR0 |
Locus tag | JMX26_RS22000 | Protein ID | WP_000079928.1 |
Coordinates | 1986..2255 (+) | Length | 90 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JMX26_RS21995 | 46..1077 | + | 1032 | WP_000907874.1 | replication initiation protein | - |
JMX26_RS22000 | 1986..2255 | + | 270 | WP_000079928.1 | hypothetical protein | Antitoxin |
JMX26_RS22005 | 2252..2533 | + | 282 | WP_000969996.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
JMX26_RS22010 | 2573..3421 | + | 849 | WP_001057996.1 | 3'-5' exonuclease | - |
JMX26_RS22015 | 3538..4011 | + | 474 | WP_001334658.1 | hypothetical protein | - |
JMX26_RS22020 | 4754..5248 | - | 495 | WP_023278058.1 | hypothetical protein | - |
JMX26_RS22025 | 5304..5906 | - | 603 | WP_000517689.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Conjugative plasmid | blaCMY-2 | - | 1..96021 | 96021 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | E9LLH3 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A5W2J4D0 |