28965

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 33492..34080 Replicon plasmid pSYSA_M
Accession NC_020287
Organism Synechocystis sp. PCC 6803

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag MYO_RS17360 Protein ID WP_011153708.1
Coordinates 33790..34080 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MYO_RS17355 Protein ID WP_011153707.1
Coordinates 33492..33779 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MYO_RS17335 (MYO_4320) 28638..28970 - 333 WP_011153703.1 DUF433 domain-containing protein -
MYO_RS19830 29023..29196 + 174 WP_158299052.1 hypothetical protein -
MYO_RS19835 29242..29391 - 150 WP_158299053.1 hypothetical protein -
MYO_RS17340 (MYO_4330) 29423..29698 + 276 WP_011153704.1 hypothetical protein -
MYO_RS17345 (MYO_4340) 29890..30084 + 195 WP_011153705.1 hypothetical protein -
MYO_RS17350 (MYO_4350) 30248..33124 + 2877 WP_011153706.1 DUF3854 domain-containing protein -
MYO_RS17355 (MYO_4360) 33492..33779 - 288 WP_011153707.1 putative addiction module antidote protein Antitoxin
MYO_RS17360 (MYO_4370) 33790..34080 - 291 WP_011153708.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MYO_RS17365 (MYO_4380) 34198..34449 + 252 WP_011153709.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
MYO_RS17370 (MYO_4390) 34440..34802 + 363 WP_011153710.1 type II toxin-antitoxin system PemK/MazF family toxin -
MYO_RS17375 (MYO_4400) 34868..35122 - 255 WP_011153711.1 DUF1819 family protein -
MYO_RS17380 (MYO_4410) 35155..35739 - 585 WP_011153712.1 hypothetical protein -
MYO_RS17385 (MYO_4420) 35732..36313 - 582 WP_011153713.1 hypothetical protein -
MYO_RS17395 (MYO_4440) 37846..38151 - 306 WP_071822682.1 putative toxin-antitoxin system toxin component, PIN family -
MYO_RS17400 (MYO_4450) 38238..38969 - 732 WP_011153716.1 DUF4386 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Non-Mobilizable plasmid - - 1..100749 100749


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-95)

Antitoxin

Uncharacterized protein HI1420

(7-92)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10872.47 Da        Isoelectric Point: 9.8740

>T28965 WP_011153708.1 NC_020287:c34080-33790 [Synechocystis sp. PCC 6803]
MIEIRQTETYARWFKSLRDCQAKARIDIRIRRLSLVNAGDVKSVGGGVSELRINYGPGYRIYFTQQGEQLIILLAGGDKQ
TQSNDITIARDLAKEL

Download         Length: 291 bp

>T28965 NC_020287:c34080-33790 [Synechocystis sp. PCC 6803]
ATGATTGAAATCCGGCAAACAGAAACCTATGCCCGTTGGTTTAAGTCTTTGCGGGATTGCCAGGCAAAAGCCCGAATTGA
TATTCGTATTCGCCGTCTATCCTTGGTTAATGCTGGGGACGTTAAGTCGGTAGGGGGTGGGGTTTCAGAACTTCGGATTA
ACTACGGCCCCGGCTATCGCATCTATTTCACCCAGCAGGGAGAACAGTTAATTATTTTGTTGGCTGGCGGCGACAAGCAG
ACCCAATCCAATGACATCACCATTGCCCGTGATTTAGCCAAAGAACTATAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10229.81 Da        Isoelectric Point: 4.3566

>AT28965 WP_011153707.1 NC_020287:c33779-33492 [Synechocystis sp. PCC 6803]
METLKTIPWDAADHLESREDMAAYLEAALEEGDPALILVALGDIARSKGMTLIAKETGLGRESLYKALSANGNPEFVTVL
KVMEALGLRLQATTL

Download         Length: 288 bp

>AT28965 NC_020287:c33779-33492 [Synechocystis sp. PCC 6803]
ATGGAAACCCTTAAAACTATCCCTTGGGATGCCGCCGATCACCTAGAAAGCCGTGAAGACATGGCCGCTTATCTCGAAGC
CGCCCTTGAAGAAGGAGACCCTGCTCTAATCCTCGTAGCGCTGGGAGACATAGCCCGTTCCAAAGGGATGACACTGATTG
CAAAGGAAACAGGATTGGGACGGGAAAGCCTCTATAAAGCCCTATCTGCCAATGGAAATCCTGAATTTGTAACGGTTTTG
AAAGTCATGGAAGCCCTAGGACTACGCCTCCAAGCCACGACACTCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References