Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 35891..36479 Replicon plasmid pSYSA
Accession NC_005230
Organism Synechocystis sp. PCC 6803 (Synechocystis PCC6803)

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag SGL_RS00805 Protein ID WP_011153708.1
Coordinates 36189..36479 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag SGL_RS00800 Protein ID WP_011153707.1
Coordinates 35891..36178 (-) Length 96 a.a.

Genomic Context

SGL_RS19375SGL_RS00785SGL_RS00790SGL_RS00795SGL_RS00810SGL_RS00815SGL_RS00780SGL_RS19380SGL_RS00800SGL_RS00805SGL_RS00820SGL_RS00825SGL_RS00830SGL_RS00845SGL_RS00850
Location: 31422..31595 (174 bp)
Type: Others
Protein ID: WP_158299052.1
Location: 31822..32097 (276 bp)
Type: Others
Protein ID: WP_011153704.1
Location: 32289..32483 (195 bp)
Type: Others
Protein ID: WP_011153705.1
Location: 32647..35523 (2877 bp)
Type: Others
Protein ID: WP_011153706.1
Location: 36597..36848 (252 bp)
Type: Others
Protein ID: WP_011153709.1
Location: 36839..37201 (363 bp)
Type: Others
Protein ID: WP_011153710.1
Location: 31037..31369 (333 bp)
Type: Others
Protein ID: WP_011153703.1
Location: 31641..31790 (150 bp)
Type: Others
Protein ID: WP_158299053.1
Location: 35891..36178 (288 bp)
Type: Antitoxin
Protein ID: WP_011153707.1
Location: 36189..36479 (291 bp)
Type: Toxin
Protein ID: WP_011153708.1
Location: 37267..37521 (255 bp)
Type: Others
Protein ID: WP_011153711.1
Location: 37554..38138 (585 bp)
Type: Others
Protein ID: WP_011153712.1
Location: 38131..38712 (582 bp)
Type: Others
Protein ID: WP_011153713.1
Location: 40245..40550 (306 bp)
Type: Others
Protein ID: WP_071822682.1
Location: 40637..41368 (732 bp)
Type: Others
Protein ID: WP_011153716.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
SGL_RS0078031037..31369-333WP_011153703.1DUF433 domain-containing protein-
SGL_RS1937531422..31595+174WP_158299052.1hypothetical protein-
SGL_RS1938031641..31790-150WP_158299053.1hypothetical protein-
SGL_RS0078531822..32097+276WP_011153704.1hypothetical protein-
SGL_RS0079032289..32483+195WP_011153705.1hypothetical protein-
SGL_RS0079532647..35523+2877WP_011153706.1DUF3854 domain-containing protein-
SGL_RS0080035891..36178-288WP_011153707.1putative addiction module antidote proteinAntitoxin
SGL_RS0080536189..36479-291WP_011153708.1type II toxin-antitoxin system RelE/ParE family toxinToxin
SGL_RS0081036597..36848+252WP_011153709.1AbrB/MazE/SpoVT family DNA-binding domain-containing protein-
SGL_RS0081536839..37201+363WP_011153710.1type II toxin-antitoxin system PemK/MazF family toxin-
SGL_RS0082037267..37521-255WP_011153711.1DUF1819 family protein-
SGL_RS0082537554..38138-585WP_011153712.1hypothetical protein-
SGL_RS0083038131..38712-582WP_011153713.1hypothetical protein-
SGL_RS0084540245..40550-306WP_071822682.1putative toxin-antitoxin system toxin component, PIN family-
SGL_RS0085040637..41368-732WP_011153716.1DUF4386 domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
insideNon-Mobilizable plasmid--1..103307103307


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-95)

Antitoxin

Uncharacterized protein HI1420

(7-92)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10872.47 Da        Isoelectric Point: 9.8740

>T21033 WP_011153708.1 NC_005230:c36479-36189 [Synechocystis sp. PCC 6803]
MIEIRQTETYARWFKSLRDCQAKARIDIRIRRLSLVNAGDVKSVGGGVSELRINYGPGYRIYFTQQGEQLIILLAGGDKQ
TQSNDITIARDLAKEL

Download         Length: 291 bp

>T21033 NC_005230:c36479-36189 [Synechocystis sp. PCC 6803]
ATGATTGAAATCCGGCAAACAGAAACCTATGCCCGTTGGTTTAAGTCTTTGCGGGATTGCCAGGCAAAAGCCCGAATTGA
TATTCGTATTCGCCGTCTATCCTTGGTTAATGCTGGGGACGTTAAGTCGGTAGGGGGTGGGGTTTCAGAACTTCGGATTA
ACTACGGCCCCGGCTATCGCATCTATTTCACCCAGCAGGGAGAACAGTTAATTATTTTGTTGGCTGGCGGCGACAAGCAG
ACCCAATCCAATGACATCACCATTGCCCGTGATTTAGCCAAAGAACTATAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10229.81 Da        Isoelectric Point: 4.3566

>AT21033 WP_011153707.1 NC_005230:c36178-35891 [Synechocystis sp. PCC 6803]
METLKTIPWDAADHLESREDMAAYLEAALEEGDPALILVALGDIARSKGMTLIAKETGLGRESLYKALSANGNPEFVTVL
KVMEALGLRLQATTL

Download         Length: 288 bp

>AT21033 NC_005230:c36178-35891 [Synechocystis sp. PCC 6803]
ATGGAAACCCTTAAAACTATCCCTTGGGATGCCGCCGATCACCTAGAAAGCCGTGAAGACATGGCCGCTTATCTCGAAGC
CGCCCTTGAAGAAGGAGACCCTGCTCTAATCCTCGTAGCGCTGGGAGACATAGCCCGTTCCAAAGGGATGACACTGATTG
CAAAGGAAACAGGATTGGGACGGGAAAGCCTCTATAAAGCCCTATCTGCCAATGGAAATCCTGAATTTGTAACGGTTTTG
AAAGTCATGGAAGCCCTAGGACTACGCCTCCAAGCCACGACACTCTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References