21033

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 35891..36479 Replicon plasmid pSYSA
Accession NC_005230
Organism Synechocystis sp. PCC 6803 (Synechocystis PCC6803)

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag SGL_RS00805 Protein ID WP_011153708.1
Coordinates 36189..36479 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag SGL_RS00800 Protein ID WP_011153707.1
Coordinates 35891..36178 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SGL_RS00780 31037..31369 - 333 WP_011153703.1 DUF433 domain-containing protein -
SGL_RS19375 31422..31595 + 174 WP_158299052.1 hypothetical protein -
SGL_RS19380 31641..31790 - 150 WP_158299053.1 hypothetical protein -
SGL_RS00785 31822..32097 + 276 WP_011153704.1 hypothetical protein -
SGL_RS00790 32289..32483 + 195 WP_011153705.1 hypothetical protein -
SGL_RS00795 32647..35523 + 2877 WP_011153706.1 DUF3854 domain-containing protein -
SGL_RS00800 35891..36178 - 288 WP_011153707.1 putative addiction module antidote protein Antitoxin
SGL_RS00805 36189..36479 - 291 WP_011153708.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SGL_RS00810 36597..36848 + 252 WP_011153709.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
SGL_RS00815 36839..37201 + 363 WP_011153710.1 type II toxin-antitoxin system PemK/MazF family toxin -
SGL_RS00820 37267..37521 - 255 WP_011153711.1 DUF1819 family protein -
SGL_RS00825 37554..38138 - 585 WP_011153712.1 hypothetical protein -
SGL_RS00830 38131..38712 - 582 WP_011153713.1 hypothetical protein -
SGL_RS00845 40245..40550 - 306 WP_071822682.1 putative toxin-antitoxin system toxin component, PIN family -
SGL_RS00850 40637..41368 - 732 WP_011153716.1 DUF4386 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Non-Mobilizable plasmid - - 1..103307 103307


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-95)

Antitoxin

Uncharacterized protein HI1420

(7-92)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10872.47 Da        Isoelectric Point: 9.8740

>T21033 WP_011153708.1 NC_005230:c36479-36189 [Synechocystis sp. PCC 6803]
MIEIRQTETYARWFKSLRDCQAKARIDIRIRRLSLVNAGDVKSVGGGVSELRINYGPGYRIYFTQQGEQLIILLAGGDKQ
TQSNDITIARDLAKEL

Download         Length: 291 bp

>T21033 NC_005230:c36479-36189 [Synechocystis sp. PCC 6803]
ATGATTGAAATCCGGCAAACAGAAACCTATGCCCGTTGGTTTAAGTCTTTGCGGGATTGCCAGGCAAAAGCCCGAATTGA
TATTCGTATTCGCCGTCTATCCTTGGTTAATGCTGGGGACGTTAAGTCGGTAGGGGGTGGGGTTTCAGAACTTCGGATTA
ACTACGGCCCCGGCTATCGCATCTATTTCACCCAGCAGGGAGAACAGTTAATTATTTTGTTGGCTGGCGGCGACAAGCAG
ACCCAATCCAATGACATCACCATTGCCCGTGATTTAGCCAAAGAACTATAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10229.81 Da        Isoelectric Point: 4.3566

>AT21033 WP_011153707.1 NC_005230:c36178-35891 [Synechocystis sp. PCC 6803]
METLKTIPWDAADHLESREDMAAYLEAALEEGDPALILVALGDIARSKGMTLIAKETGLGRESLYKALSANGNPEFVTVL
KVMEALGLRLQATTL

Download         Length: 288 bp

>AT21033 NC_005230:c36178-35891 [Synechocystis sp. PCC 6803]
ATGGAAACCCTTAAAACTATCCCTTGGGATGCCGCCGATCACCTAGAAAGCCGTGAAGACATGGCCGCTTATCTCGAAGC
CGCCCTTGAAGAAGGAGACCCTGCTCTAATCCTCGTAGCGCTGGGAGACATAGCCCGTTCCAAAGGGATGACACTGATTG
CAAAGGAAACAGGATTGGGACGGGAAAGCCTCTATAAAGCCCTATCTGCCAATGGAAATCCTGAATTTGTAACGGTTTTG
AAAGTCATGGAAGCCCTAGGACTACGCCTCCAAGCCACGACACTCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References